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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Nitrated keyhole limpet hemocyanin (KLH).
- 亚型:
Nitrotyrosine Antibody
- 形态:
Nitrotyrosine Antibody
- 保存条件:
提供的Nitrotyrosine抗体(HM11)产品为无色溶液形式,含有50 ug抗体.该产品浓度为0.5 mg/ml,溶解于不含防腐剂的无菌溶液中.请在收到该Nitrotyrosine抗体(HM11)产品后,将其置于-20 °C冷冻保存,建议分装使用以避免反复冻融.
- 克隆性:
单克隆
- 标记物:
Nitrotyrosine Antibody
- 适应物种:
Western Blot (1 ug/ml) using secondary antibody coupled to alkaline phosphatase and BCIP/NBT as substrate, ELISA (1:1000), Immunohistochemistry.
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 抗原来源:
Nitrated keyhole limpet hemocyanin (KLH).
- 目录编号:
Nitrotyrosine Antibody
- 级别:
Nitrotyrosine Antibody
- 库存:
Nitrotyrosine Antibody
- 供应商:
艾美捷
- 宿主:
小鼠
- 应用范围:
Western Blot (1 ug/ml) using secondary antibody coupled to alkaline phosphatase and BCIP/NBT as substrate, ELISA (1:1000), Immunohistochemistry.
- 浓度:
Nitrotyrosine Antibody
- 靶点:
Nitrotyrosine Antibody
- 抗体英文名:
Nitrotyrosine Antibody
- 抗体名:
硝基酪氨酸抗体
- 规格:
50ug
产品名称:硝基酪氨酸抗体/硝基酪氨酸抗体/硝基酪氨酸抗体-Nitrotyrosine Antibody /Nitrotyrosine Antibody /Nitrotyrosine Antibody
产品货号:5414-50-E 产品规格:50ug 应用类型:Western Blot (1 ug/ml) using secondary antibody coupled to alkaline phosphatase and BCIP/NBT as substrate, ELISA (1:1000), Immunohistochemistry.
保存建议:硝基酪氨酸抗体/硝基酪氨酸抗体/硝基酪氨酸抗体-Nitrotyrosine Antibody /Nitrotyrosine Antibody /Nitrotyrosine Antibody 提供的Nitrotyrosine抗体(HM11)产品为无色溶液形式,含有50 ug抗体.该产品浓度为0.5 mg/ml,溶解于不含防腐剂的无菌溶液中.请在收到该Nitrotyrosine抗体(HM11)产品后,将其置于-20 °C冷冻保存,建议分装使用以避免反复冻融.
背景资料:Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species such as peroxynitrite anion and nitrogen dioxide. It is a marker for inflammation and nitric oxide (NO) production. It is detected in large number of pathological conditions and is considered a marker of NO-dependent, reactive nitrogen species-induced nitrative stress. Tyrosine nitration can inactivate enzymes and receptors that depend on tyrosine residues for their activity. Nitration prevents phosphorylation of tyrosine residues important for signal transduction. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques, chronic renal failure and keratoconus. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine Antibody detects proteins and peptides containing nitro-tyrosine in a manner independent of the surrounding amino acid sequence. It is a valuable tool for identifying new nitrated proteins as well as for assaying protein nitration and measuring levels of nitrated proteins in tissues and samples.
点击:硝基酪氨酸抗体/硝基酪氨酸抗体/硝基酪氨酸抗体-Nitrotyrosine Antibody /Nitrotyrosine Antibody /Nitrotyrosine Antibody 查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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关键词:Nitrotyrosine Antibody /Nitrotyrosine Antibody /Nitrotyrosine Antibody ,硝基酪氨酸抗体/硝基酪氨酸抗体/硝基酪氨酸抗体,Nitrotyrosine
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文献和实验High‐Throughput, Multiplexed Analysis of 3‐Nitrotyrosine in Individual Proteins
on the microarray chips. Then, a monoclonal antibody for 3?nitrotyrosine is used to detect the amount of 3?nitrotyrosine on each spot. Our studies suggest that this approach can be used to detect trace amounts of 3?nitrotyrosine in human plasma and sputum
Analysis of Oxidative Modification of Proteins
Primary antibody: mouse anti‐nitrotyrosine antibodies (Upstate Biotechnology) Secondary antibody: rabbit anti‐mouse IgG conjugated with alkaline phosphatase
Proteomic Method for Identification of Tyrosine-Nitrated Proteins
Biologic nitration of protein tyrosine (to form 3-nitrotyrosine) is a recently described phenomenon that is associated with many diseases. We have devised a proteomic methodology to identify these modified proteins. This utilizes protein
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