FADD Antibody，FAS-associated d
eath domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1- 询价
- BioVision
- 美国
- 3039-100
- 2025年07月13日
- Western blot analysis （0.5-4 ug/ml）and can also be used in immunoprecipitation. However， the optimal conditions should be determined individually. The antibody detects an ~28 kDa band， corresponding to the expected molecular mass of FADD on immunoblots.
- 兔
- Western blot analysis （0.5-4 ug/ml）and can also be used in immunoprecipitation. However， the optimal conditions should be determined individually. The antibody detects an ~28 kDa band， corresponding to the expected molecular mass of FADD on immunoblots.
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide surrounding amino acid 128 of human FADD
- 亚型：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 形态：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 保存条件：
提供的FADD抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该FADD抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
- 克隆性：
单克隆
- 标记物：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 适应物种：
Western blot analysis （0.5-4 ug/ml）and can also be used in immunoprecipitation. However， the optimal conditions should be determined individually. The antibody detects an ~28 kDa band， corresponding to the expected molecular mass of FADD on immunoblots.
- 保质期：
根据订购时间与产品批次判定，欢迎联系艾美捷咨询确认
- 抗原来源：
Synthetic peptide surrounding amino acid 128 of human FADD
- 目录编号：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 级别：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 库存：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 供应商：
艾美捷
- 宿主：
兔
- 应用范围：
Western blot analysis （0.5-4 ug/ml）and can also be used in immunoprecipitation. However， the optimal conditions should be determined individually. The antibody detects an ~28 kDa band， corresponding to the expected molecular mass of FADD on immunoblots.
- 浓度：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 靶点：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 抗体英文名：
FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
- 抗体名：
FADD抗体
- 规格：
100ug
产品名称：FADD抗体/FADD抗体/FADD抗体-FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1
产品货号：3039-100-E 产品规格：100ug 应用类型：Western blot analysis （0.5-4 ug/ml）and can also be used in immunoprecipitation. However， the optimal conditions should be determined individually. The antibody detects an ~28 kDa band， corresponding to the expected molecular mass of FADD on immunoblots.
保存建议：FADD抗体/FADD抗体/FADD抗体-FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 提供的FADD抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该FADD抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
背景资料：Fas-associating death domain containing protein （FADD）， also known as mediator of receptor induced toxicity （MORT1）， is a 23 kDa cytosolic protein with an apparent molecular weight of 28 kDa on SDS-PAGE. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas to initiate the apoptotic signalling cascade. Overexpression of FADD induces apoptosis.
点击：FADD抗体/FADD抗体/FADD抗体-FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。
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关键词：FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 /FADD Antibody，FAS-associated death domain protein，GIG3，MGC8528，MORT1 ，FADD抗体/FADD抗体/FADD抗体，FADD
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文献和实验Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
years. For the CD95 and the TRAIL-R1/R2 DISCs, it is now clear that the adaptor protein Fas-associated DD protein (FADD) forms part of these complexes and is necessary for recruitment of the pro-apoptotic signaling molecules caspase-8 and caspase
内的死亡域（DD）结合Fas结合蛋白FADD（fas associated protein with DD），FADD再以其N端的死亡效应子域（death effector domain，DED）结合Pro-Caspase-8（或-10），形成一个由Fas-FADD-Pro-Caspase-8（或-10）三种分子组成的复合体，称为诱导死亡的信号复合体（death inducing signaling complex，DISC），其中Pro-Caspase-8（或-10）就可以自身催化
to remove transformed cells and virus infected cells. Binding of FAS to oligimerized FasL on another cell activates apoptotic signaling through a cytoplasmic domain termed the death domain that interacts with signaling adaptors including FAF, FADD and DAX
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