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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human UDP-glucose 6-dehydrogenase (UGDH)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Human UDP-glucose 6-dehydrogenase (UGDH)品名简称:
Recombinant Human UGDH protein货号:
CSB-EP025567HU规格:
20μg价格:
1344LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
UGDHUniprot No.:
O60701别名:
GDH; UDP Glc dehydrogenase; UDP GlcDH; UDP glucose 6 dehydrogenase; UDP glucose dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDP-glucose dehydrogenase; UDPGDH; UGD; Ugdh; UGDH_HUMAN; Uridine diphospho glucose dehydrogenase种属:
Homo sapiens (Human)蛋白长度:
Full Length来源:
E.coli分子量:
71 kDa表达区域:
1-494aa氨基酸序列:
MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIPKFSLQDPPNKKPKV蛋白标签:
N-terminal 6xHis-SUMO-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.功能2:
Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.文献:
Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011)研究领域:
Cell Biology请点击“在线询价”找客服索取产品说明书及引用文献目录,产品实时更新参数、价格信息、更多文献信息可以查看cusabio官网
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文献和实验二磷酸尿苷葡糖 uridine diphosphate glucose
一般简称UDP-萄糖或UDPG等。系广泛分布于微生物、动植物细胞内的核苷酸糖的一种,在UDP-葡萄糖焦磷酸化酶(UDP glucose pyrophosphor-ylase,EC 2.7.7.9)的作用下由UTP和1-磷酸-α-D-葡糖生物合成。在生物体内,当各种苷、寡糖、多糖的生物合成时用作葡萄糖的供体。此外,在单糖的互变或糠醛酸生成时作为重要的中间产物,而在碳水化合物代谢中起着中心的作用。
机制有助于为早期发现肿瘤转移提供生物标志物,为干涉转移提供新策略,从而取得更好的预后。代谢失调是癌症的标志,癌基因和肿瘤抑制基因的突变会引起多种细胞内信号通路的改变,使肿瘤细胞重新设计以提高生存和生长力。独特的生物化学微环境进一步影响肿瘤细胞代谢表型,进而影响肿瘤的进展、对治疗的反应和患者的预后。本研究揭示了UDP-glucose对肿瘤转移的独特影响,提出了代谢物调节蛋白功能的新模型,建立了代谢与RNA稳定性之间的新关联。实验结果表明,经过表皮生长因子受体(EGFR)活化,磷酸化的UGDH与HuR相互
领域奠基之作:Cell 重磅报道可胞外展示的糖基化修饰 RNA——glycoRNA
唾液酸形式 Neu5Ac 和 Neu5Gc。而当样品被 VC-Sia 或 RNase 处理时,则检测不到,进一步证实 glycoRNA 被唾液酸修饰的。 图片来源:Cell 经典的 N - 多糖合成机制有助于 glycoRNA 的产生 蛋白质上有两类主要的多糖,N - 多糖和 O - 多糖,两者都可以被唾液酸化。 研究人员使用遗传学、药理学和酶学的结合方法进行检测,探索 glycoRNA 结构是否与糖蛋白相关多糖结构相关。 IdID CHO 细胞系不能产生 UDP-Gal 和 UDP
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