- 询价
- Agrisera
- 瑞典
- AS16 3164
- 2025年10月17日
- 2 µg/ml (Dot), 1 : 500 (ELISA), 2.5 µg/IP (hMeDIP)
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
BSA-conjugated molecule: 5-hydroxymethylcytosine (5-hmC).
- 亚型：
IgG1k
- 形态：
Liquid
- 保存条件：
Store lyophilized/reconstituted at -20°C; for long
- 克隆性：
Monoclonal
- 适应物种：
Human
- 级别：
分子生物学级
- 供应商：
Agrisera
- 宿主：
Mouse
- 应用范围：
2 µg/ml (Dot), 1 : 500 (ELISA), 2.5 µg/IP (hMeDIP)
- 靶点：
5-hmC | 5-hydroxymethylcytosine is a recently discovered DNA modification which results from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of oxygenases. It may have an important roles distinct from that of 5-
- 抗体名：
5-hmC | 5-hydroxymethylcytosine (monoclonal)
- 规格：
100 µg
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文献和实验Investigating 5-Hydroxymethylcytosine (5hmC): The State of the Art
The discovery of 5-hydroxymethylcytosine (5hmC) as an abundant base in mammalian genomes has excited the field of epigenetics, and stimulated an intense period of research activity aimed at decoding its biological significance
Cell Reports：浙大蒋晞课题组发文揭示阿片受体激动剂调控白血病表观遗传学修饰的新机制
拷贝数异常等，已无法完全解释 AML 复杂的病理表现和预后；而表观遗传学调控则是在遗传学基础上的进一步精细调整。蒋晞研究团队近年的研究发现，这类微调往往能在白血病的发生发展、药物反应等方面起到决定性作用[2-6]。因此，进一步研究表观遗传学调控在白血病中的作用机制，以及开发干预表观遗传调控的治疗白血病的新途径具有重要意义。 TET (Ten-eleven translocation) 家族蛋白 TET1/2/3 可介导 DNA 发生 5-羟甲基胞嘧啶 (5-hydroxymethylcytosine
Hydroxymethylated DNA Immunoprecipitation (hmeDIP)
5-hydroxymethylcytosine (5hmC) was recently identified as an abundant epigenetic mark in mammals. Subsequent research has implicated 5hmC in normal mammalian development and disease pathogenesis in humans. Many of the techniques commonly used
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