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IAPP | Human IAPP (amylin) 1-3

7, specific for the native hormone having a disulphide-bridge between Cys2-Cys7
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  • 询价
  • Agrisera
  • 瑞典
  • AS08 359
  • 2025年11月10日
  • 1:1000 (WB), 1:1000 (ELISA)
  • Chicken
  • Human
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    • 详细信息
    • 技术资料
    • 免疫原

      Synthetic peptide corresponding to the human the 37 residue IAPP also known as amylin. The IAPP/amylin peptide contains a disulphide-bridge between Cys2-Cys7 Amino acid sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (disulphide link between Cys2-Cys7)

    • 形态

      Lyophilized

    • 保存条件

      Store lyophilized/reconstituted at -20°C; once rec

    • 克隆性

      Polyclonal

    • 适应物种

      Human

    • 级别

      分子生物学级

    • 供应商

      Agrisera

    • 宿主

      Chicken

    • 应用范围

      1:1000 (WB), 1:1000 (ELISA)

    • 靶点

      Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is co

    • 抗体英文名

      Antibody is specific for the native hormone having a disulphide-bridge between Cys2-Cys7.

    • 抗体名

      IAPP | Human IAPP (amylin) 1-37, specific for the native hormone having a disulphide-bridge between Cys2-Cys7

    • 规格

      50 µl

    Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.

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    IAPP | Human IAPP (amylin) 1-37, specific for the native hormone having a disulphide-bridge between Cys2-Cys7
    询价