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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Fucose
- 抗体英文名:
Fucose
- 靶点:
This antibody specifically cross-reacts against fucose residues bound to the protein N-glycans in alpha 1,3. This residue is characterisitc of the plant protein N-glycans and is absent in protein N-glycans from animals. This residue is added in the Golgi
- 应用范围:
ELISA (ELISA), Immunolocalization (IL), Western blot (WB)
- 宿主:
Rabbit
- 适应物种:
Higher plants, Pheodactylum tricornutum (diatom)
- 级别:
Affinity purified serum in PBS, pH 7.4
- 供应商:
Agrisera AB
- 克隆性:
单克隆
- 保存条件:
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the ca
- 形态:
Lyophilized
- 免疫原:
core fucose residues bound to the N-glycan in alpha 1,3
- 规格:
50 µg
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文献和实验Fucose-Targeted Glycoengineering of Pharmaceutical Cell Lines
Glycosylation is known to have an impact on pharmacokinetics and pharmacodynamics of therapeutic proteins. While the production of pharmaceutically desirable glycosylation forms of a therapeutic protein can in certain cases be influenced
N-Glycans with an α-fucose unit linked to the 6-position of the innermost GlcNAc are widely distributed among the animal kingdom, from worms and insects to human. This α1,6-linked fucosyl residue, frequently referred to as a core fucose
Deglycosylation of Glycoproteins Using Endoglycosidases
(CHO)-N-S-D-I-S-S-T-R IGM, biantennary with core 1-6 fucose, Sodium acetate 100 mM pH 4.5 Protocol: 1. Heat denature transferrin by incubation of 1 mg/ml of the glycoprotein in 0.5% SDS for 3 min. at 90°C.
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