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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human Factor VIIa (NovoSeven ®, Novo Nordisk A/S Denmark)
- 形态:
Lyophilized in PBS pH 7.4
- 保存条件:
Store lyophilized/reconstituted at -20°C; once rec
- 克隆性:
Polyclonal
- 标记物:
Lopez-Vilchez et al. (2009). Traffic of rFVIIa through Endothelial Cells and Redistribution into Subendothelium: Implications for a Prolonged Hemostatic Effect. Journal of Coagulation Disorders, October 1: (1). (immunolocalization)
- 适应物种:
Human
- 抗原来源:
Q9FI56 , Q9SXJ7
- 级别:
分子生物学级
- 供应商:
Agrisera
- 宿主:
Rabbit
- 应用范围:
1 : 15 000 (I-ELISA), 14 µg/ml (IL)
- 靶点:
Factor VIIa (FVIIa) is a key serine protease involved in the initiation of the coagulation cascade. FVIIa requires tissue factor (TF), a membrane bound protein, as an essential cofactor for maximal activity towards its biological substrates Factor X, Fact
- 抗体英文名:
This antibody is purified using Protein G, to obtain a total IgG fraction.
- 抗体名:
FVIIa | Coagulation factor VIIa (50 µg)
- 规格:
50 µg
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文献和实验Tissue Factor/VIIa in Thrombosis and Cancer
Tissue factor (TF) is a transmembrane glycoprotein that functions as a receptor and cofactor for activated factor VII (factor VIIa) to initiate blood coagulation. Although TF has been characterized best for its role in blood coagulation
Studies on Coagulation Incompatibilities for Xenotransplantation
) circulating PC in the presence of thrombin. Tissue factor pathway inhibitor (TFPI), is the primary inhibitor of tissue factor (TF)-induced coagulation. TFPI directly inhibits the activated factor X (FXa) and blocks the procoagulant activity of the TF/factor
Tissue Factor Pathway Inhibitor in Thrombosis and Beyond
of various diseases. In recent years, tissue-factor pathway inhibitor (TFPI), the only endogenous inhibitor of the TF/FVIIa complex, has been characterized biochemically and pharmacologically. Studies in patients have demonstrated that both TF and TFPI
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