人GLI2重组蛋白GLI family zinc finge
r protein 2 Tax helper proteinHuman Zinc finger protein GLI2（GLI2)蛋白- ￥1344
- CUSABIO
- CN
- CSB-EP009500HU
- 2026年01月20日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期：
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名：
Recombinant Human Zinc finger protein GLI2 (GLI2), partial
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 规格：
20μg
英文名称：
Recombinant Human Zinc finger protein GLI2 (GLI2), partial品名简称：
Recombinant Human GLI2 protein, partial货号：
CSB-EP009500HU规格:
20μg价格：
1344LC-MS/Western Blot：
/SDS-PAGE：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度：
Greater than 90% as determined by SDS-PAGE.内毒素：
Not test生物活性：
/基因名：
GLI2Uniprot No.：
P10070别名：
GLI family zinc finger protein 2 Tax helper protein种属：
Homo sapiens (Human)蛋白长度：
Partial来源：
E.coli分子量：
42.5 kDa表达区域：
412-641aa氨基酸序列：
EQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCL蛋白标签：
N-terminal 6xHis-SUMO-tagged产品提供形式：
Liquid or Lyophilized powder缓冲液：
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件：
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期：
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期：
13-23 business days注意事项：
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1：
Functions as transcription regulator in the hedgehog (Hh) pathway (PubMed:18455992). Functions as transcriptional activator (PubMed:9557682, PubMed:19878745, PubMed:24311597). May also function as transcriptional repressor (By similarity). Requires STK36 for full transcriptional activator activity. Required for normal embryonic development (PubMed:15994174, PubMed:20685856).功能2：
Functions as transcription regulator in the hedgehog (Hh) pathway文献：
"Novel heterozygous nonsense GLI2 mutations in patients with hypopituitarism and ectopic posterior pituitary lobe without holoprosencephaly."Franca M.M., Jorge A.A., Carvalho L.R., Costalonga E.F., Vasques G.A., Leite C.C., Mendonca B.B., Arnhold I.J.J. Clin. Endocrinol. Metab. 95:E384-E391(2010) .研究领域：
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文献和实验ARF GTPase-Activating Protein 1
of intrinsic GTPase activity, and GTP hydrolysis depends on the action of GTPase-activating proteins (GAPs). ARF GAPs are a family of proteins which contain a conserved GAP domain of approx 130 amino acids with a unique Cys4 zinc-finger motif near their amino
Yeast Two-Hybrid Screening for Proteins Interacting With the Anti-Apoptotic Protein A20
by the detection of binding partners for the zinc finger protein A20. The latter is an inducible cellular inhibitor of tumor necrosis factor (TNF)-induced apoptosis and nuclear factor (NF)-κB-dependent gene expression. Yeast two-hybrid screening with A20 as bait
, a zinc finger protein whose expression is induced by agents that activate NF-kB. A20 functions to block TRAF2-mediated NF-kB activation. A20 also inhibits TNF and IL-1 induced activation of NF-kB suggesting that it may act as a general inhibitor of NF
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