APCS|APCS蛋白|APCS猪蛋白|APCS Pig P

APCS（SAP）分子特征、免疫调控机制与相关疾病及靶向治疗进展

血清淀粉样蛋白P成分（APCS/SAP/PTX2）是五聚体蛋白家族的重要成员，作为一种钙依赖性凝集素，它能与DNA、组蛋白及凋亡碎片等多种分子相互作用，协助清除受损细胞释放的核物质。依托重组蛋白、抗体开展的体外实验证实，SAP在淀粉样变性、纤维化及心血管疾病等多种免疫相关疾病的诊断与治疗中，发挥着灵敏的生物标志物作用。此外，作为一种关键的免疫调节因子，SAP还能结合细菌多糖、淀粉样沉积物和病毒蛋白，参与先天免疫调节。 APCS的表达分布 血清淀粉样蛋白P成分（APCS），它主要由肝细胞合成

Analysis of MicroRNA and Protein Transfer by Exosomes During an Immune Synapse

of exosomes produced by immune cells by ultracentrifugation, their quantification by flow cytometry, and the analysis of miRNA and protein exchange between T cells and APCs, both at a distance and after the formation of an immune synapse.

T-Lymphocyte Activation Induced by Staphylococcal Enterotoxin Superantigens: Analysis of Protein Tyrosine Phosphorylation

lymphocytes by binding simultaneously to TCR Vβ domains and to major histocompatibility complex (MHC) class II molecules on antigen-presenting cells (APCs) (1 ). Several characteristics distinguish enterotoxin superantigens from conventional antigens