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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Rat Parathyroid hormone (Pth)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Rat Parathyroid hormone (Pth)品名简称:
Recombinant Rat Pth protein货号:
CSB-EP018987RA规格:
20μg价格:
2328LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 85% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
PthUniprot No.:
P04089别名:
Parathyrin种属:
Rattus norvegicus (Rat)蛋白长度:
Full Length of Mature Protein来源:
E.coli分子量:
16.9 kDa表达区域:
32-115aa氨基酸序列:
AVSEIQLMHNLGKHLASVERMQWLRKKLQDVHNFVSLGVQMAAREGSYQRPTKKEENVLVDGNSKSLGEGDKADVDVLVKAKSQ蛋白标签:
N-terminal 10xHis-tagged and C-terminal Myc-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).功能2:
/文献:
"Nucleotide sequences of parathyroid gene in five species of macaque of Thailand." Malaivijitnond S., Takenaka O. J. Sci. Res. Chulalongkorn Univ. 23:135-142(1998)研究领域:
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文献和实验甲状旁腺激素(parathyroid hormone,PTH)
甲状旁腺主细胞分泌的肽类激素。正常人血浆PTH含量约1毫微克/毫升,最高可达6毫微克/毫升。其主要靶器官是骨、肾和小肠,调节钙、磷代谢,最终效应是升血钙,降低血磷:(1)对骨的作用。PTH刺激骨质吸收,动员骨的钙、磷入血。可分为快速效应和慢速效应两个时相。快速效应数分钟内即可发生,作用于骨细胞膜系统。骨细胞膜系统是由骨细胞和成骨细胞组成的一层膜,除破骨细胞邻近的区域外,覆盖全部骨表面和腔隙表面,从而在骨质与细胞外液之间形成可通透性屏障。这层膜与骨质之间有少量滑液,细胞外液侧
北京时间 2022 年 2 月 9 日,中国科学院深圳先进技术研究院脑认知与脑疾病研究所、深港脑科学创新研究院杨帆课题组在 Nature Communications 上发表题为 An optogenetic approach for regulating human parathyroid hormone secretion 的最新研究成果。 研究团队历时 5 年,创新性地将光遗传技术运用于甲状旁腺素(Parathyroid Hormone, PTH)的分泌调控,通过精准节律性调节
In Vivo Parathyroid Hormone Treatments and RNA Isolation and Analysis
Intermittent parathyroid hormone (PTH) administration increases bone formation and bone mass and is being used as a therapy for osteoporosis. By contrast, chronic hyperparathyroidism results in the metabolic bone disease osteitis fibrosa
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