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MedChemExpress LLC
- CAS号:
2112731-48-1
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询盘
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N-(Biotin-PEG4)-N-bis(PEG4-acid)
CAS No. : 2112731-48-1
MCE 国际站:N-(Biotin-PEG4)-N-bis(PEG4-acid)
产品活性:N-(Biotin-PEG4)-N-bis(PEG4-acid) 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
研究领域:PROTAC
作用靶点:PROTAC Linkers
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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文献和实验Protein Carbonyl Determination Using Biotin Hydrazide
functions represent a variety of site-specific modifications, most particularly adipic and glutamic acid semialdehydes (2 ). Additionally, numerous lipid oxidation products, including αβ-unsaturated γ-hydroxyalkenals can attack proteins yielding protein
Preparation of nucleic acid probes
Preparation of nucleic acid probes In standard nucleic acid hybridization assays the probe is labeled in some way. Nucleic acid probes may be made as single-stranded or double-stranded molecules (see Figure 5.1 ), but the working probe
hapten- or biotin-labeled probe (an indirect label). This type of indirect approach has been widely used with probes labeled with molecules, such as fluorescein, biotin, and digoxygenin. An example of such a system using fluorescein-labeled probes
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