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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1268488-70-5
- 规格：
100 mg/250 mg/1 g/5 g
| 规格： | 100 mg | 产品价格： | ￥224.0 |
|---|---|---|---|
| 规格： | 250 mg | 产品价格： | ￥341.0 |
| 规格： | 1 g | 产品价格： | ￥1358.0 |
| 规格： | 5 g | 产品价格： | ￥5010.0 |
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Bis-PEG9-acid
CAS No. : 1268488-70-5
MCE 国际站：Bis-PEG9-acid
产品活性：Bis- PEG9- acid 是一种 PROTAC linker，属于 PEG 类。Bis- PEG9- acid 可用于合成一系列 PROTAC 分子。Bis- PEG9- acid 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联活性分子 (ADCs) 的合成。
研究领域：PROTAC | Antibody-drug Conjugate/ADC Related
作用靶点：PROTAC Linkers | ADC Linker
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
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文献和实验James Hardwick CNBr Cleavage Procedure
tube containing 200 microliters of 100mg/ml CNBr in 70% formic acid. CNBr stocks are 200 milligrams/ml in 70% formic acid and are stored at -70°C. 70% formic acid is made from 98-100% formic acid and MQH2O. Optional: If you want to know
, 2.2M dNTP’s 100mM EDTA 0.5M EtBr 10mg/ml Gelatin 2% Glucose 1; 1.5; 2M Guanidine HCl 1-8M HEPES 1M Imidazol 2M Paraformaldehyde 37% PEG 40% PMSF 100mM Retinoic acid 10mM Sucrose 1; 2; 2.5M Tris Cl 1M
the pellet in 10 ml sterile 1 X TE/LiAC (made fresh from stocks of 10 X TE [0.1 M Tris-HCI, 0.01 M EDTA, pH 7.5] and 10X LiAC [1 M lithium acetate adjusted to pH 7.5 with dilute acetic acid]. Repeat. Pellet cells in microfuge at 7000rpm, discard sup
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