A peptide corresponding to the residues in human CD29 (Integrin beta-1).
内容
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
浓度
500 ug/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
保存条件
12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
Integrin beta-1, also known as CD29, is a protein that in humans is encoded by the ITGB1 gene. CD29 is an integrin unit associated with very late antigen receptors. It is known to conjoin with alpha-3 subunit to create alpha3beta1 complex that reacts to such molecules as netrin-1 and reelin. This gene contains a beta subunit that appears to be analogous to band-3 of integrin. It is mapped to 10p11.22. It is found that FER mediates crosstalk between CDH2 and CD29. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. The protein encoded by this gene is a beta subunit.
研究类别
1. Goodfellow PJ, Nevanlinna HA, Gorman P, Sheer D, Lam G, Goodfellow PN (July 1989). "Assignment of the gene encoding the beta-subunit of the human fibronectin receptor (beta-FNR) to chromosome 10p11.2". Ann Hum Genet53 (Pt 1): 15–22.2. Pytela, R., Pierschbacher, M. D., Ginsberg, M. H., Plow, E. F., Ruoslahti, E. Platelet membrane glycoprotein IIb/IIIa: member of a family of arg-gly-asp-specific adhesion receptors. Science 231: 1159-1162, 1986.
[list_product_images]Figure 1. Western Blotting result
Western Blot of HeLa cell lysates using anti-CD29 rabbit monoclonal antibody (clone RM285) at a 1:4000 dilution.|Figure 2. IHC result
Immunohistochemical staining of formalin fixed and paraffin embedded human brain tissue sections using anti-CD29 rabbit monoclonal antibody (clone RM285) at a 1:200 dilution.|Figure 3. IHC result
Immunohistochemical staining of formalin fixed and paraffin embedded human colon tissue sections using anti-CD29 rabbit monoclonal antibody (clone RM285) at a 1:200 dilution.[/list_product_images]