A peptide corresponding to residues near the N-terminus of human BAG-1L
内容
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
浓度
500 ug/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
保存条件
12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
BAG family molecular chaperone regulator 1(BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.
研究类别
1. Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC (Mar 1995). "Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity". Cell 80 (2): 279–84. 2. Takayama, S., Kochel, K., Irie, S., Inazawa, J., Abe, T., Sato, T., Druck, T., Huebner, K., Reed, J. C.Cloning of cDNAs encoding the human BAG1 protein and localization of the human BAG1 gene to chromosome 9p12.Genomics35: 494-498, 1996.3. "Entrez Gene: BAG1 BCL2-associated athanogene".
[list_product_images]Figure 1. Western Blotting result
Western Blot of HeLa cell lysate, using anti-BAG-1L rabbit monoclonal antibody (Clone RM310) at a 1:1000 dilution.|Figure 2. IHC result
Immunohistochemical staining of formalin fixed and paraffin embedded 22RV1 cell section using anti-BAG-1L rabbit monoclonal antibody (Clone RM310) at a 1:2000 dilution.|Figure 3. IHC result
Immunohistochemical staining of formalin fixed and paraffin embedded 22RV1 cell section using anti-BAG-1L rabbit monoclonal antibody (Clone RM310) at a 1:2000 dilution.|Figure 4. IHC result
Immunohistochemical staining of formalin fixed and paraffin embedded BAG-1L overexpressing LNCaP cell section using anti-BAG-1L rabbit monoclonal antibody (Clone RM310) at a 1:2000 dilution.[/list_product_images]