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- 详细信息
- 技术资料
- 库存:
大量
- 供应商:
PeproTech(派普泰克)
- 英文名:
Recombinant Human Furin
Recombinant Human Furin
产品编号:
450-47
别名:
FUR, PACE, PCSK3
描述:
Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Furin is a calcium dependent serine endoprotease that processes numerous proproteins of different secretory pathways into their mature forms by cleaving at the carboxyl side of the recognition sequence, R-Xaa-(K/R)-R, where Xaa can be any amino acid. Recombinant human Furin is a 61.7 kDa protein, corresponding to residues 124 through 715 of the Furin precursor plus a C-terminal His tag.
氨基酸序列:
DLNVKAAWAQ GYTGHGIVVS ILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNAR IGGVRMLDGE VTDAVEARSL GLNPNHIHIY SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFV WASGNGGREH DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ IVTTDLRQKC TESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT SKPAHLNAND WATNGVGRKV SHSYGYGLLD AGAMVALAQN WTTVAPQRKI IDILTEPKDI GKRLEVRKTV TACLGEPNHI TRLEHAQARL TLSYNRRGDL AIHLVSPMGT RSTLLAARPH DYSADGFNDW AFMTTHSWDE DPSGEWVLEI ENTSEANNYG TLTKFTLVLY GTAPEGLPVP PESSGCKTLT SSQACVVCEE GFSLHQKSCV QHCPPGFAPQ VLDTHYSTEN DVETIRASVC APCHACSATC QGPALTDCLS CPSHASLDPV EQTCSRQSQS SRESPPQQQP PRLPPEVEAG QRLRAGLLPS HLPEHHHHHH HH
来源:
Hi-5 Insect cells
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Measured by its ability to cleave the fluorogenic peptide substrate Boc-Arg-Val-Arg-Arg-AMC (Bachem Catalog# I-1645.0025).
原产国:
USA
仅用于研究。不适用于诊断或治疗。
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PeproTech重组人Furin 2ug
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