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- Cytoskeleton
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- 2025年07月07日
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文献和实验to tumorigenesis or other diseases. For this reason, the identification of small, cell permeable molecules capable of inhibition of Rho GTPases can be extraordinarily useful, particularly if they are specific and act reversibly.
target Rho-kinase is crucial for spontaneous migration of Walker carcinosarcoma cells. We now show that after treatment of cells with either the Rho inhibitor C3 exoenzyme or the Rho-kinase inhibitor Y-27632, constitutive myosin light chain (MLC
Assessment of Drug Transporter Function Using Fluorescent Cell Imaging
of transporters in clinical pharmacokinetics has shed light on the need for in vitro screening methods that detect drug?transporter interactions during preclinical development. This unit describes cell?based procedures for detecting functional inhibitors of BCRP
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