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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
NPL4
- 浓度:
1 mg/mL.
- 应用范围:
WB
- 宿主:
Rabbit
- 适应物种:
Human, Rat, Mouse
- 保质期:
1年
- 供应商:
Huabio
- 标记物:
Non-conjugated
- 保存条件:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 形态:
Liquid
- 亚型:
IgG
- 免疫原:
Synthesized peptide derived from human protein . at AA range: 270-350
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2500.0 |
domain:Binds ubiquitinated proteins via its RanBP2-type zinc finger. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. pathway:Protein degradation; proteasomal ubiquitin-dependent pathway. Belongs to the NPL4 family. Contains 1 RanBP2-type zinc finger. subcellular location:Associated with the endoplasmic reticulum and nuclear. subunit:Heterodimer with UFD1L. The heterodimer binds ubiquitinated proteins. The heterodimer binds to VCP and inhibits Golgi membrane fusion. tissue specificity:Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver.
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ER60944·Anti-NPL4 Antibody
¥1500 - 2500








