Coronavirus spike重组蛋白|Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD Recombinant Protein
- ￥4500 - 37830
- Sino Biological
- 北京
- 40592-VNAH
- 2025年08月12日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD Recombinant Protein
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/100.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥37830.0 |
|---|---|---|---|
| 规格： | 100.00 µg | 产品价格： | ￥4500.0 |
新冠病毒S RBD蛋白具有如下的特点：
1. 新冠病毒S RBD蛋白有编码SARS-COV-2 spike protein的RBD片段基因(YP_009724390.1) (Arg319-Phe541)表达。不带标签。
2. 新冠病毒S RBD蛋白经SDS-PAGE电泳检测，蛋白纯度> 95 %。
3. 新冠病毒S RBD蛋白利用LAL方法检测，内毒素含量低于1.0 EU/μg 。
4. 新冠病毒S RBD蛋白由HEK293细胞表达，接近天然结构，活性高。
5. 新冠病毒S RBD蛋白活性检测结果显示，蛋白具有良好的ACE2结合活性。
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- 询问日期
文献和实验2, Kramer KJ, et al. Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition.Cell reports, PubMed ID: 34592170
3, Gebre MS, et al. Optimization of Non-Coding Regions for a Non-Modified mRNA COVID-19 Vaccine.Nature, PubMed ID: 34794169
4, Alameh MG, et al. Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses.Immunity, PubMed ID: 34852217
5, Kurmangali A, et al. Sensitive Detection of SARS-CoV-2 Variants Using an Electrochemical Impedance Spectroscopy Based Aptasensor.International journal of molecular sciences, PubMed ID: 36361926
6, Wang H, et al. Establishment of angiotensin-converting enzyme 2 and cluster of differentiation 147 dual target cell membrane chromatography based on SNAP-tag technology for screening anti severe acute respiratory syndrome coronavirus 2 active components.Journal of chromatography. A, PubMed ID: 36870232
7, Gary EN, et al. Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge.Frontiers in immunology, PubMed ID: 36999023
8, Ozawa T, et al. Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1.Structure (London, England : 1993), PubMed ID: 38228146
Targeted RNA recombination has proven to be a powerful tool for the genetic engineering of the coronavirus genome, particularly in its 3′ part. Here we describe procedures for the generation of recombinant and mutant mouse hepatitis virus
Science：老药新用，研究发现癌症药物马赛替尼可有效对抗
近日，来自芝加哥大学的研究团队在 Science 上发表了一篇题为 Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 的文章。该研究结果表明，酪氨酸酶抑制剂马赛替尼在抑制新冠病毒复制活性，减轻肺部炎症方面有显著的效果，并且体外实验表明马赛替尼对于新冠病毒的多种变种（B.1.1.7, B.1.351 and P.1）也具有作用。图片来源：Science研究内容随着全球疫苗
of PBS-T/BSA with more specialized solutions in serologic assays for antibodies against the RBD of SARS-CoV-2 (Fig. 5). While the signal intensity in a positive sample is comparable, background from negative samples - serum samples taken
