产品名称
SARS-CoV-2 (2019-nCoV) Spike S2 Antibody, Chimeric MAb
经验证的应用
ELISA (Antibody's applications have not been validated with corresponding viruses. Optimal concentrations/dilutions should be determined by the end user.)
应用说明
(Antibody's applications have not been validated with corresponding viruses. Optimal concentrations/dilutions should be determined by the end user.)
特异性
2019-nCoV Coronavirus spike
No cross-reactivity in ELISA with
SARS-CoV-2 (2019-nCoV) Spike S1 (Cat# 40591-V08H)
SARS-CoV-2 (2019-nCoV) Spike RBD (Cat# 40592-V05H)
免疫原
Recombinant SARS-CoV-2 / 2019-nCoV Spike S2 ECD Protein (Catalog#40590-V08B)
制备方法
It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified, recombinant SARS-CoV-2 Spike S2 ECD Protein. The antibody was produced using recombinant antibody technology.
来源
Monoclonal mouse (variable region) / human (kappa / IgG1 constant) chimeric antibody Clone #D001
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
1, Wang, Z; et al. ACE2 can act as the secondary receptor in the FcγR-dependent ADE of SARS-CoV-2 infection. iScience
2, Escalera, A; et al. Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission. Cell Host & Microbe
3, Duty, JA; et al. Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants. Med (New York, N.Y.), Pubmed: 36044897