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- 2025年07月12日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
D-Norgestrel
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
797-63-7
- 规格：
10 mM * 1 mL/100 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥330.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥300.0 |
| 规格： | 500 mg | 产品价格： | ￥450.0 |
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Levonorgestrel
CAS No. : 797-63-7
MCE 国际站：Levonorgestrel
产品活性：Levonorgestrel 是一种口服有效的孕酮 (HY-N0437) 抑制剂。Levonorgestrel 具有抗癌活性，能够诱导细胞凋亡。Levonorgestrel 能够用于避孕且能与其他药物进行联用。Levonorgestrel 能够用于骨质疏松、子宫平滑肌瘤的研究。
研究领域：Apoptosis
作用靶点：Apoptosis | Caspase | Bcl-2 Family | Survivin
In Vitro: Levonorgestrel (5-25 mg/mL; 72 h) inhibits cell proliferation and promotes apoptosis in uterine leiomyoma cells in a concentration-dependent manner.
Levonorgestrel (0.1-100 μM; 4 h) doesn’t affect progesterone production at low doses (0-10 μM), but can inhibit progesterone production at high doses (100 μM) in luteal cells.
In Vivo: Levonorgestrel (0.005-0.15 mg/kg; Once every two days for three weeks) can inhibit bone resorption, decrease bone turnover, and increase bone mineral content in Sprague-Dawley rats.
Levonorgestrel (1 mg/kg; Intragastric administration; Once daily for three days) provides effective contraception for Apodemus agrarius mice in combination with quinestrol (HY-B1012).
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