HDAC-IN-4,1252003-13-6

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HDAC-IN-4

CAS No. : 1252003-13-6

MCE 国际站：HDAC-IN-4

产品活性：HDAC-IN-4 是一种选择性的 HDAC6 和 HDAC10 抑制剂，在 BRET 实验中，对 HDAC6 和 HDAC10 的 pIC₅₀ 分别为 7.2 和 6.8。具有抗肿瘤活性。

研究领域：Cell Cycle/DNA Damage  |  Epigenetics

作用靶点：HDAC

In Vitro: HDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC₅₀s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET assay, respectively.
HDAC-IN-4 is more potent against HDAC6 than Tubastatin A, suggests that HDAC-IN-4 may be a better HDAC6 probe than Tubastatin A.

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