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- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
2067332-64-1
- 规格:
10 mM * 1 mL/1 mg/5 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥4150.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥2050.0 |
| 规格: | 5 mg | 产品价格: | ¥5120.0 |
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USP30 inhibitor 11
CAS No. : 2067332-64-1
MCE 国际站:USP30 inhibitor 11
产品活性:USP30 inhibitor 11 是一个选择性和有效的 USP30 抑制剂,IC50 值为 0.01 µΜ。USP30 inhibitor 11 是例 83,源于专利文献 WO2017009650A1,用于研究癌症和涉及线粒体功能障碍疾病。
研究领域:Cell Cycle/DNA Damage
作用靶点:Deubiquitinase
In Vitro: USP30 is a 517 amino acid protein which is found in the mitochondrial outer membrane. It is the sole deubiquitylating enzyme bearing a mitochondrial addressing signal and has been shown to deubiquitylate a number of mitochondrial proteins.
USP30 inhibitor 11 (0.01-30 µΜ; λEx=540 nm; λEm=590 nm) inhibits USP30 biochemical activity with an IC50 of 0.01 µΜ in a USP30 biochemical IC50 assay.
相关产品:Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Ubiquitination Compound Library | Heterocyclic Compound Library | Cysteine Targeted Covalent Library | Highly Selective Inhibitors Library | BAY 11-7082 | N-Ethylmaleimide | PR-619 | Spautin-1 | ML-323 | KSQ-4279 | Degrasyn | P005091 | 6-Thioguanine | IU1 | b-AP15 | Capzimin | ML364 | USP25/28 inhibitor AZ1 | LDN-57444 | DUB-IN-2 | GRL0617 | P 22077 | EOAI3402143 | GSK2643943A | MF-094 | XL177A | CMPD-39 | FT206 | GNE-6776 | USP5-IN-1 | GNE-6640 | SJB3-019A | IU1-47 | Thiolutin
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文献和实验测序法分析p16/CDKN2基因CpG岛甲基化状态;(10)RESULTS:DNA sequence analysis proved correct reconstruction of A53T and A30P.(10)结果:DNA测序结果证明构建载体插入正确α-突触核蛋白突变体A53T与A30P基因。(11)METHODS: RKO cells were treated with selective DNA methyltransferase (DNMTs) inhibitor, 5-Aza-2′
。 2. 接种密度:传代比例 1:2 ~ 1:4,70% - 80% 汇合度时传代。 3. 控制胰酶消化时间:避免过长损伤细胞。 4. 冻存复苏温度要求:冻存缓慢降温,复苏快速升温,减少损伤。 5. 复苏后换液原则:24 小时后首次换液,避免频繁操作。 H22 细胞 小鼠肝癌细胞,分离自小鼠腹水,为悬浮细胞,呈淋巴母细胞样[10]。 培养条件:RPMI-1640培养基,10% 胎牛血清,1% 青霉素链霉素双抗[11]。 注意事项:
) Sodium azide 18.4 mg% (w/v) Dinitrophenol (DNP) 6.64% (w/v) Sodium Malonate 10% (w/v) KOH Procedure When you enter the lab, check that the reference chambers of the Gilson respirometer
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