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货期：询盘
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5 mg (26.28 mM * 500 μL in Methyl acetate)/10 mg (26.28 mM * 1 mL in Methyl acetate)
| 规格： | 5 mg (26.28 mM * 500 μL in Methyl acetate) | 产品价格： | ￥3200.0 |
|---|---|---|---|
| 规格： | 10 mg (26.28 mM * 1 mL in Methyl acetate) | 产品价格： | ￥5100.0 |
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16,16-Dimethyl prostaglandin E2
CAS No. : 39746-25-3
MCE 国际站：16,16-Dimethyl prostaglandin E2
产品活性：16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) 是一种具有口服活性的脊椎动物造血干细胞 (HSCs) 稳态关键调节剂。16,16-Dimethyl prostaglandin E2 可以通过 EP2/EP4 起作用，并与 Wnt 途径相互作用。
研究领域：GPCR/G Protein
作用靶点：Prostaglandin Receptor
In Vivo: 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2; 10 μg/kg; i.p.; every 12 hours; for 8 days) rescues the exacerbated DSS colitis phenotype of Tpl2IMF-KO mice and restores epithelial proliferation and structure.
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文献和实验Abrogation of the RB-p16Tumor Suppressor Pathway in Human Lung Cancer
of this late G1 restriction point is the protein product of the retinoblastoma gene, pRB (1). In its hypophosphorylated form, pRB binds E2F-family transcription factors. Functional inactivation of pRB leads to release of these transcription factors
Osteoclast Formation in Mouse Co-cultures
The murine co-culture assay is used to generate mature osteoclasts from bone marrow precursors by culturing them with osteoblasts that are stimulated with 1,25-dihydroxy vitamin D3 and prostaglandin E2 . This assay is used particularly
Generation of Osteoclasts In Vitro, and Assay of Osteoclast Activity
are formed in response to various osteotropic factors such as 1α,25-dihydroxyvitamin D3 , parathyroid hormone, prostaglandin E2 , and interleukin -11. Recent studies have revealed that osteoblasts express two cytokines essential for osteoclastogenesis
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