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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2797-51-5
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥188.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥171.0 |
| 规格： | 10 mg | 产品价格： | ￥233.0 |
| 规格： | 25 mg | 产品价格： | ￥361.0 |
| 规格： | 50 mg | 产品价格： | ￥500.0 |
| 规格： | 100 mg | 产品价格： | ￥800.0 |
| 规格： | 500 mg | 产品价格： | ￥2038.0 |
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Quinoclamine
CAS No. : 2797-51-5
MCE 国际站：Quinoclamine
产品活性：Quinoclamine 是一种萘醌衍生物，是一种 NF-κB 抑制剂。Quinoclamine 具有抗肿瘤活性。
研究领域：NF-κB
作用靶点：NF-κB
In Vitro: Quinoclamine causes differentiation of U-937 cells into macrophage-like cells.
Quinoclamine inhibits NF-κB activities in HepG2 cells, with an IC50 of 1.7 μM.
Quinoclamine (1-4 μM; 30 minutes ) suppresses endogenous NF-κB activity in HepG2 cells through the inhibition of IκB-α phosphorylation and p65 translocation.
Quinoclamine inhibits induced NF-κB activities in lung and breast cancer cell lines.
Quinoclamine affects the expression levels of genes involved in cell cycle or apoptosis.
Quinoclamine down-regulates the expressions of UDP glucuronosyltransferase genes involved in phase II drug metabolism.
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