D-赤型-二氢鞘氨醇-1-磷酸|D-erythro-Dihy

D-赤型-二氢鞘氨醇-1-磷酸，D-erythro-Dihydrosphingosine-1-phosphate，D-erythro-Dihydrosphingosine-1-phosphate

产品名称：D-赤型-二氢鞘氨醇-1-磷酸-D-erythro-Dihydrosphingosine-1-phosphate

产品货号：1852-5

产品规格：5mg

背景资料：Dihydrosphingosine-1-phosphate (DhS1P) is the saturated analog of the more common sphingosine-1-phosphate (S1P) and has recently been found to have many important and unique functions. It has been found to activate ERK1/2 and to stimulate MMP1 production. DhS1P induces MMP1 (a key enzyme in matrix degradation) while S1P does not1 and S1P enhances TGF-beta through cross-activation of Smad signaling while DhS1P inhibits it.2 DhS1P or its derivatives have been suggested as effective therapeutic antifibrotic agents. Because of their unique actions in vivo DhS1P can be used as a negative control for S1P for intracellular effects. However, DhS1P is a ligand for many S1P receptors. It has been found that SK1 overexpression, but not SK2, in different primary cells and cultured cell lines results in predominant upregulation of the synthesis of DhS1P compared to S1P. A new functional role for SK1 has been presented, which can control the survival/death (DhS1P-S1P/ceramides) balance by targeting sphingolipid de novo biosynthesis and selectively generating DhS1P at a metabolic step preceding ceramide formation.3

保存建议：D-赤型-二氢鞘氨醇-1-磷酸-D-erythro-Dihydrosphingosine-1-phosphate对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：D-erythro-Sphinganine-1-phosphate

点击：D-赤型-二氢鞘氨醇-1-磷酸-D-erythro-Dihydrosphingosine-1-phosphate查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多Matreya公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。

Matreya LLC是一家脂质生化公司，致力于开发和制造高质量的脂质和生物化学品。Matreya在化学合成以及天然产物提取和纯化方面经验丰富，生产出的产品具有最佳纯度。 Matreya产品线包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和维生素E异构体（生育酚和生育三烯酚）。专长是生产高纯度鞘氨醇、神经酰胺、硫酸酯、神经节苷脂、酶抑制剂、生育酚和生育三烯酚。是全球提供脂质产品最全的供应商之一。产品涉及生物化学、制药、微生物学、食品和农业等研究领域。

艾美捷科技有限公司，通过提供完整的产品和服务体系、便利的客户关系和供应链管理，为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观:“学习、创新、合作、卓越"。作为一家具有尖端的技术实力、的经营管理水平和完善的市场销售体系的生物高科技企业，总部位于武汉光谷高新技术开发区，服务面向全国。艾美捷科技是集进口试剂、实验室耗材销售、技术服务与合约开发为一体的专业化高科技公司，为用户提供最前沿的专业资讯、完备的产品、整合的解决方案，及优质的物流服务。为了更好的服务客户，公司组建了一支经验丰富的研发团队-艾美捷生物技术中心，进入研发生产阶段，将更优质的产品推荐给国内生物领域的同仁们!