N-乙酰-D-赤型-C14鞘脂碱基|N-Acetyl-D-e

N-乙酰-D-赤型-C14鞘脂碱基，N-Acetyl-D-erythro-C14 sphingolipid base，N-Acetyl-D-erythro-C14 sphingolipid base

产品名称：N-乙酰-D-赤型-C14鞘脂碱基-N-Acetyl-D-erythro-C14 sphingolipid base

产品货号：1842-5

产品规格：5mg

背景资料：N-Acetyl-D-erythro-C14-sphingosine is a well-defined ceramide and is ideal for use as a standard and in biological studies. This product has the C14 sphingoid base, which is less prevalent than the C18 base in most plants and animals making it very useful in determining sphingosine metabolism and derivatives and as an internal standard. Natural long-chain ceramide functions as a precursor in the synthesis of sphingomyelin, glycosphingolipids, and of free sphingosine and fatty acids. It also exerts numerous biological effects, including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, and cell death.1 N-Acetyl-D-erythro-C16-sphingosine enters easily into cells where it is biologically active and has been shown to induce downregulation of Bcl-2 protein, inhibiting cell proliferation and inducing apoptosis.2 N-Acetylsphingosine demonstrates many of the biological activities associated with ceramides that contain long-chain fatty acids. However, it has also been found that N-acetyl-sphingosine may inhibit neutrophil superoxide release,3 stimulation of DNA synthesis, and phospholipase D activity. N-acetyl-sphingosine is different from sphingosine as seen by its inability to inhibit protein kinase C or cause calcium release.

保存建议：N-乙酰-D-赤型-C14鞘脂碱基-N-Acetyl-D-erythro-C14 sphingolipid base对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：N-C2:0-Ceramide of D-erythro-C14-sphingosine

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