Isocurcumenol,24063-71-6

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Isocurcumenol

CAS No. : 24063-71-6

MCE 国际站：Isocurcumenol

产品活性：Isocurcumenol 可从 Curcuma zedoaria Rhizomes 中分离得到，是 ERα 的抑制剂。具有抗肿瘤活性。其对 DLA 和 KB 癌细胞的 IC₅₀ 分别为 99.1 µg/mL 和 178.2 µg/mL。

研究领域：Vitamin D Related/Nuclear Receptor  |  Apoptosis

作用靶点：Estrogen Receptor/ERR  |  Apoptosis

In Vitro: Isocurcumenol (12.5-400 µg/mL, 24-48 h) dose-dependently inhibits cancer cells proliferation.
isocurcumenol does not exhibit any significant toxicity on normal chicken embryo fibroblast cells and lymphocytes.

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