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- 2025年12月05日
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-20°C, protect from light
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货期：1-2天
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MedChemExpress LLC
- CAS号：
120926-46-7
- 规格：
1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 1 mg | 产品价格： | ￥400.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥900.0 |
| 规格： | 10 mg | 产品价格： | ￥1440.0 |
| 规格： | 25 mg | 产品价格： | ￥2463.0 |
| 规格： | 50 mg | 产品价格： | ￥3663.0 |
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Isoliquiritin apioside
CAS No. : 120926-46-7
MCE 国际站：Isoliquiritin apioside
产品活性：Isoliquiritin apioside 显著降低了 PMA 诱导的 MMP9 活性增加，并抑制了 PMA 诱导的 MAPK 和 NF-κB 活化。Isoliquiritin apioside 抑制癌细胞和内皮细胞的侵袭和血管生成。
研究领域：NF-κB | Metabolic Enzyme/Protease | MAPK/ERK Pathway
作用靶点：NF-κB | MMP | p38 MAPK
In Vitro: Isoliquiritin apioside efficiently suppresses the PMA-induced gelatinolytic MMP-9 activity in HT1080 cells. Isoliquiritin apiosidealso decreases the PMA-induced increase in MMP-9 production in HT1080 cells.Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and endothelial cells (ECs), with no cytotoxicity.
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