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- 保存条件:
4°C, protect from light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
5041-81-6
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥828.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥350.0 |
| 规格: | 5 mg | 产品价格: | ¥900.0 |
| 规格: | 10 mg | 产品价格: | ¥1530.0 |
| 规格: | 25 mg | 产品价格: | ¥3050.0 |
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Isoliquiritin
CAS No. : 5041-81-6
MCE 国际站:Isoliquiritin
产品活性:Isoliquiritin 是从甘草根中分离得到的,能抑制血管生成和导管形成。Isoliquiritin 还具有抗抑郁\抗氧化,抗炎作用和抗真菌活性。
研究领域:Anti-infection
作用靶点:Fungal
In Vitro: Isoliquiritin (0-400 μg/mL) inhibits the growth of a panel of plant pathogenic fungi.
Isoliquiritin (0-100 μg/mL, 4 h) inhibits sporangia germination of P. litchii.
Isoliquiritin (20 μM, 24 h) protects cell from Corticosterone (400 μM)-induced apoptosis in PC12 cells, and reduces LDH release, increases the activity of SOD, CAT, decreases the ROS and MDA level.
In Vivo: Isoliquiritin (0.31-3.1 mg/kg, i.p., once a day for 5 days) inhibits granuloma angiogenesis in mice.
Isoliquiritin (10-40 mg/kg, oral gavage) shows antidepressant-like effects in FST and TST tests in mice.
Isoliquiritin ((10 mg/kg/bw/day, p.o.) shows anti-oxidative and anti-Inflammatory properties, and relieves cationic BSA-Induced membranous glomerulonephritis in experimental rat model.
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文献和实验Overview of Animal Models of Obesity
Coleman, D.L. and Eicher, E.M. 1990. Fat (fat) and tubby (tub): Two autosomal recessive mutations causing obesity syndromes in the mouse. J. Hered. 81:424‐427. Corander, M.P
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