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- MedChemExpress(MCE)
- 美国
- HY-W007713
- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Fmoc-NH-PEG2-CH2COOH
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
166108-71-0
- 规格：
1 g/5 g/10 g/25 g/100 g
| 规格： | 1 g | 产品价格： | ￥100.0 |
|---|---|---|---|
| 规格： | 5 g | 产品价格： | ￥180.0 |
| 规格： | 10 g | 产品价格： | ￥280.0 |
| 规格： | 25 g | 产品价格： | ￥544.0 |
| 规格： | 100 g | 产品价格： | ￥2116.0 |
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Fmoc-8-amino-3,6-dioxaoctanoic acid
CAS No. : 166108-71-0
MCE 国际站：Fmoc-8-amino-3,6-dioxaoctanoic acid
产品活性：Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) 是一种可降解的 ADC linker，用于抗体活性分子偶联物 (ADC) 合成。Fmoc-8-amino-3,6-dioxaoctanoic acid 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。
研究领域：Antibody-drug Conjugate/ADC Related | PROTAC
作用靶点：ADC Linker | PROTAC Linkers
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
相关产品：5-Ethynyl-2'-deoxyuridine | DSS Crosslinker | Mc-Val-Cit-PABC-PNP | TGN-020 | NH2-C2-NH-Boc | SMCC | DBCO-NHS ester | Sulfo-SMCC sodium | MC-Val-Cit-PAB | DBCO-PEG4-NHS ester | L-Azidohomoalanine hydrochloride | N-Boc-piperazine | DSG Crosslinker | DSP Crosslinker | Val-cit-PAB-OH | Fmoc-3VVD-OH | 3-Mercaptopropionic acid NHS ester | Alkynyl Palmitic Acid | Boc-NH-PEG3 | Amino-PEG3-C2-Azido | Biotin-PEG3-azide | SPDP | Fmoc-Val-Cit-PAB | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | Fmoc-Val-Cit-PAB-PNP | MAC glucuronide linker-2 | NH2-PEG2-C6-Cl | Maleimide-DOTA | N3-PEG4-C2-NHS ester | 3,6-Dioxaoctanedioic acid
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
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文献和实验Solid-Phase Synthesis of Neuropeptides by Fmoc Strategies
an automated peptide synthesizer that performs solid-phase peptide synthesis using the Fmoc strategy (1 ). This is based on the sequential addition of amino acid residues to an insoluble polymeric support. The base-labile Fmoc group
) to check derivatisation and chromatography efficiency and to allow quantitation of samples. Note that the Fmoc-amino acid derivatives are stable for 24 h, allowing many samples to be prepared in advance and loaded onto an autosampler for injection
Synthesis of C-Terminal Peptide Thioesters Using Fmoc-Based Solid-Phase Peptide Chemistry
This chapter provides two protocols for the solid-phase synthesis of peptide thioesters using N α -Fmoc-protected amino acids. The first protocol is based on a so-called safety-catch linker, while the second relies on a backbone amide
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