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- 保存条件:
Pure form: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
1043884-49-6
- 规格:
100 mg/250 mg/500 mg/1 g
| 规格: | 100 mg | 产品价格: | ¥544.0 |
|---|---|---|---|
| 规格: | 250 mg | 产品价格: | ¥1151.0 |
| 规格: | 500 mg | 产品价格: | ¥2225.0 |
| 规格: | 1 g | 产品价格: | ¥2886.0 |
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m-PEG6-azide
CAS No. : 1043884-49-6
MCE 国际站:m-PEG6-azide
产品活性:m-PEG6-azide 是一种不可降解 (non-cleavable) 的含 6 个单元 PEG 的 ADC linker,可用于合成抗体偶联活性分子 (ADC)。m-PEG6-azide 是一种点击化学试剂。它含有 Azide 基团,可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应(CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。
研究领域:Antibody-drug Conjugate/ADC Related
作用靶点:ADC Linker
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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文献和实验Monoclonal Antibody Production Protocol
the PEG. Do not disturb the cells. Spin at 1000 rpm for 5 min. Aspirate medium, resuspend cells by tapping. Slowly add 5 ml of 37°C IMDM-m. Bring to 20 ml and add to the flask in the incubator. (If using feeder cells, add them at this point; 106 cells
. After adding , swirl the tube gently to mix and dilute the PEG. Do not disturb the cells. Spin at 1000 rpm for 5 min. Aspirate medium, resuspend cells by tapping. Slowly add 5 ml of 37°C IMDM-m. Bring to 20 ml and add to the flask
to the Cu(I)?catalyzed ?click chemistry? with a variety of azide compounds for highly specific, internal modification of RNA. Curr. Protoc. Nucleic Acid Chem. 48:4.49.1?4.49.16. © 2012 by John Wiley & Sons, Inc. Keywords: 2??deoxy
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