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- 详细信息
- 文献和实验
- 技术资料
- 库存:
72
- 英文名:
Recombinant Murine Breast and Kindey-expressed Chemokine/CXCL14
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冷冻(-20℃)
- 规格:
5μg
特别提示:包括重组小鼠BRAK/CXCL14在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组小鼠BRAK/CXCL14
英文名称:Recombinant Murine Breast and Kindey-expressed Chemokine/CXCL14
产品货号:GS4727
产品规格:5μg
分子量:Approximately 9.4kDa,a single non-glycosylated polypeptide chain containing 77amino acids.
储存条件:冷冻(-20℃)
概述
Chemokine(C-X-C motif)ligand 14(CXCL14),also named BRAK,is a small cytokine belonging to the CXC chemokine family.It is constitutively expressed at the mRNA level in certain normal tissues and it possesses chemoattractive activity for activated macrophages,immature dendritic cells and natural killer cells.According to the relevant literature,CXCL14 is associated with tumor development.Moreover,recent evidence revealed that CXCL14 participates in glucose metabolism,feeding behaviour-associated neuronal circuits,and anti-microbial defense.Although CXCL14 receptors have not yet been identified,the intracellular activity of CXCL14 in breast cancer cells suggests that the CXCL14 receptor(s)and signal transduction pathway(s)may be different from those of conventional CXC-type chemokines.Recombinant murine CXCL14 contains 77 amino acid residues and it shares 97%and 99%a.a.sequence identity with human and rat CXCL14.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | >95%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,400 mM NaCl,pH 7.4,5%trehalose. |
| 内毒素 | Less than 1 EU/μg of rMuBRAK/CXCL14 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤-20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIVTTKS MSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE |
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文献和实验一个近交系进行数次回次(通常回交2次),再经无对特殊基因选择的近亲交配而育成的近交系。 2.1.5.2 命名 a) 重组近交系的命名 由两个亲代近交系的缩写名称中间加大写英文字母X命名。由相同双亲交配育成的一组近交系用阿拉拍数字予以区分。 例如:由BALB/c与C57BL两个近交系杂交育成的一组重组近交系,分别命名为CXB1、CXB2…… 对常用近交系小鼠的缩写名称规定如下: 近交系 缩写名称 C57BL/6 B6 BALB/C C DBA
系的命名 由两个亲代近交系的缩写名称中间加大写英文字母X命名。由相同双亲交配育成的一组近交系用阿拉拍数字予以区分。 例如:由BALB/c与C57BL两个近交系杂交育成的一组重组近交系,分别命名为CXB1、CXB2…… 对常用近交系小鼠的缩写名称规定如下: 近交系 缩写名称 C57BL/6 B6
系的命名 由两个亲代近交系的缩写名称中间加大写英文字母X命名。由相同双亲交配育成的一组近交系用阿拉拍数字予以区分。 例如:由BALB/c与C57BL两个近交系杂交育成的一组重组近交系,分别命名为CXB1、CXB2…… 对常用近交系小鼠的缩写名称规定如下: 近交系 缩写名称 C57BL/6 B6
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