重组人TFF3北京厂家

特别提示：包括重组人TFF3在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人TFF3
英文名称：Recombinant Human Trefoil Factor 3
产品货号：GS4843
产品规格：5μg

分子量：Approximately 6.6kDa,a single non-glycosylated polypeptide chain containing 59 amino acids,which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
储存条件：冷冻（-20℃）

概述

Trefoil factor 3 encoded by the TFF3 gene in humans,belongs to the trefoil factor family that consists of three members named TFF1,TFF2 and TFF3.They are characterized by having at least one copy of the trefoil motif,a 40-amino acid domain that contains three conserved disulfides.TFF-3 is expressed by goblet cells and in the uterus,and has also been shown to express in certain cancers,including colorectal,hepatocellular,and in biliary tumors.It involves in the maintenance and repair of the intestinal mucosa,also promotes the mobility of epithelial cells in healing processes.TFF3 overexpression is crucial for progression in mouse and human hepatocellular carcinogenesis.TFF3 may be useful as a molecular marker for certain types of cancer,but its role,if any,in tumorigenesis is unknown.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10μg/ml,corresponding to a specific activity of>100 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuTFF3 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF

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