蛋白酶磷酸酶抑制剂混合物(哺乳动物样品抽提用, 50X)

1. Minglei Zhi, Jinying Zhang, Qianzi Tang, Dawei Yu, Shuai Gao, Dengfeng Gao, Pengliang Liu, Jianxiong Guo, Tang Hai, Jie Gao, Suying Cao, Zimo Zhao, Chongyang Li, Xiaogang Weng, Mengnan He, Tianzhi Chen, Yingjie Wang, Keren Long, Deling Jiao, Guanglei Li, Jiaman Zhang, Yan Liu, Yu Lin, Daxin Pang, Qianqian Zhu, Naixin Chen, Jingjing Huang, Xinze Chen, Yixuan Yao, Jingcang Yang, Zicong Xie, Xianya Huang, Mengxin Liu, Ran Zhang, Qiuyan Li, Yiliang Miao, Jianhui Tian, Xingxu Huang, Hongsheng Ouyang, Bofeng Liu, Wei Xie, Qi Zhou, Hongjiang Wei, Zhonghua Liu, Caihong Zheng, Mingzhou Li, Jianyong Han . Generation and characterization of stable pig pregastrulation epiblast stem cell lines Cell Res. 2022 Apr;32(4):383-400. doi: 10.1038/s41422-021-00592-9. (IF 20.507)
2. Chaojie Huang, Senhao Zhou, Chaolei Zhang, Yifeng Jin, Gao Xu, Liangjing Zhou, Guoping Ding, Tianshu Pang, Shengnan Jia, Liping Cao . ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer Cancer Lett. 2022 Apr 1:530:16-28. doi: 10.1016/j.canlet.2022.01.013. (IF 7.36)
3. Wei Luo, Jiaxin Dai, Jianmin Liu, Yongmei Huang, Ziqiong Zheng, Pei Xu, Yi Ma . PACAP attenuates hepatic lipid accumulation through the FAIM/AMPK/IRβ axis during overnutrition Mol Metab. 2022 Nov:65:101584. doi: 10.1016/j.molmet.2022.101584. (IF 6.448)
4. Shicheng Sun, Taihong Gao, Bo Pang, Xiangsheng Su, Changfa Guo, Rui Zhang, Qi Pang . RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m6A-dependent manner Cell Death Dis. 2022 Jan 21;13(1):73. doi: 10.1038/s41419-022-04524-2. (IF 6.304)
5. Yan Wei, Haowan Zhang, Qiaohui Feng, Shumin Wang, Youcheng Shao, Jie Wu, Ge Jin, Weiwei Lin, Xinxin Peng, Xiaoyan Xu . A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer Cell Death Dis. 2022 Apr 2;13(4):294. doi: 10.1038/s41419-022-04734-8. (IF 6.304)
6. Shicheng Sun, Changfa Guo, Taihong Gao, Dengzhen Ma, Xiangsheng Su, Qi Pang, Rui Zhang . Hypoxia Enhances Glioma Resistance to Sulfasalazine-Induced Ferroptosis by Upregulating SLC7A11 via PI3K/AKT/HIF-1 α Axis Oxid Med Cell Longev. 2022 Nov 18:2022:7862430. doi: 10.1155/2022/7862430. (IF 5.076)
7. Luo C, Zhao S, Dai W, Zheng N, Wang J . Proteomic analyses reveal GNG12 regulates cell growth and casein synthesis by activating the Leu-mediated mTORC1 signaling pathway. BBA-PROTEINS PROTEOM. 2018 Nov;1866(11):1092-1101. (IF 2.371)
8. Zhu E, Chen W, Qin Y, Ma S, Fan S, Wu K, Li W, Fan J, Yi L, Ding H, Chen J, Zhao M . Classical Swine Fever Virus Infection Induces Endoplasmic Reticulum Stress-Mediated Autophagy to Sustain Viral Replication in vivo and in vitro. Front Microbiol. 2019 Nov 12 10:2545. (IF 4.235)
9. Hui Shi, Xiaoyu Liu, Yanwei Wang, Haiyan Wang, Bochen Pan, Jianyuan Li . Activation of the JAK1/STAT1 signaling pathway is associated with peroxiredoxin 6 expression levels in human epididymis epithelial cells Folia Histochem Cytobiol. 2022;60(3):226-236. doi: 10.5603/FHC.a2022.0021.
10. Xin Liu, Wu Luo, Jiahao Chen, Chenghong Hu, Rumbidzai N Mutsinze, Xu Wang, Yanmei Zhang, Lijiang Huang, Wei Zuo, Guang Liang, Yi Wang . USP25 Deficiency Exacerbates Acute Pancreatitis via Up-Regulating TBK1-NF-κB Signaling in Macrophages Cell Mol Gastroenterol Hepatol. 2022;14(5):1103-1122. doi: 10.1016/j.jcmgh.2022.07.013.
11. Zheng Pang, Yan Xu, Qingjun Zhu . Early Growth Response 1 Suppresses Macrophage Phagocytosis by Inhibiting NRF2 Activation Through Upregulation of Autophagy During Pseudomonas aeruginosa Infection Front Cell Infect Microbiol. 2022 Jan 12:11:773665. doi: 10.3389/fcimb.2021.773665.
12. Aihua Yu, Shun Wang, Yiqiao Xing, Mengyao Han, Kun Shao . 7,8-Dihydroxyflavone alleviates apoptosis and inflammation induced by retinal ischemia-reperfusion injury via activating TrkB/Akt/NF-kB signaling pathway Int J Med Sci. 2022 Jan 1;19(1):13-24. doi: 10.7150/ijms.65733. (IF 2.523)
13. Huihong Jiang, Erjiang Tang, Ying Chen, Hailong Liu, Yun Zhao, Moubin Lin, Luwei He . Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression Cancer Sci. 2022 Mar;113(3):971-985. doi: 10.1111/cas.15248. (IF 4.966)
14. Hua Huang, Ruining Pan, Yue Zhao, Huan Li, Huiyu Zhu, Sijia Wang, Aamir Ali Khan, Juan Wang, Xinhui Liu . L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy iScience. 2022 Apr 13;25(5):104249. doi: 10.1016/j.isci.2022.104249.
15. Ying Xia, Yong Jin, Daxiang Cui, Xia Wu, Cunfeng Song, Weilin Jin, Hai Huang . Antitumor Effect of Simvastatin in Combination With DNA Methyltransferase Inhibitor on Gastric Cancer via GSDME-Mediated Pyroptosis Front Pharmacol. 2022 Apr 20:13:860546. doi: 10.3389/fphar.2022.860546. (IF 4.225)
16. Ping Tang, Jianfeng Sheng, Xiujuan Peng, Renfei Zhang, Tao Xu, Jun Hu, Yuexi Kang, Baiyi Wu, Hao Dang . Targeting NOX4 disrupts the resistance of papillary thyroid carcinoma to chemotherapeutic drugs and lenvatinib Cell Death Discov. 2022 Apr 8;8(1):177. doi: 10.1038/s41420-022-00994-7.
17. Songlin Fang, Lezeng Wang, Chunmei Luo, Hang Yi, Xiangrui Wang, Bo Ning . Curcumol inhibits the growth of xenograft-tumors in mice and the biological activities of pancreatic cancer cells by regulating the miR-21-5p/SMAD7 axis Cell Cycle. 2022 Jun;21(12):1249-1266. doi: 10.1080/15384101.2022.2046983. (IF 3.699)
18. Chen Chen, Jiulong Ma, Zhiping Xu, Liang Chen, Bo Sun, Yan Shi, Yujia Miao, Tianlong Wu, Meng Qin, Yang Zhang, Ming Zhang, Xia Cao . Rosmarinic Acid Inhibits Platelet Aggregation and Neointimal Hyperplasia In Vivo and Vascular Smooth Muscle Cell Dedifferentiation, Proliferation, and Migration In Vitro via Activation of the Keap1-Nr J Agric Food Chem. 2022 Jun 22;70(24):7420-7440. doi: 10.1021/acs.jafc.2c01176.
19. Yuhuan Cui, Meihong Liu, Li Zuo, Haiyan Wang, Jian Liu . Fraxetin protects rat brains from the cerebral stroke via promoting angiogenesis and activating PI3K/Akt pathway Immunopharmacol Immunotoxicol. 2022 Jun;44(3):400-409. doi: 10.1080/08923973.2022.2052893.
20. Jian Luo, Jinzhi Xu, Chaolu Xie, Zuoming Zhao, Junrui Guo, Yuan Wen, Tian Li, Zeyang Zhou . Microsporidia Promote Host Mitochondrial Fragmentation by Modulating DRP1 Phosphorylation Int J Mol Sci. 2022 Jul 13;23(14):7746. doi: 10.3390/ijms23147746. (IF 4.556)
21. Chan Liu, Zhipei Sang, Hong Pan, Qin Wu, Yu Qiu, Jingshan Shi . A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer's Disease by Dual Inhibition of Acetylcholinesterase and Inflammation Front Aging Neurosci. 2022 Jul 4:14:922650. doi: 10.3389/fnagi.2022.922650. (IF 4.362)
22. Yafang Du, Deming Li, Jingsi Chen, Yun-Hong Li, Zixiang Zhang, Khemayanto Hidayat, Zhongxiao Wan, Jia-Ying Xu, Li-Qiang Qin . Lactoferrin improves hepatic insulin resistance and pancreatic dysfunction in high-fat diet and streptozotocin-induced diabetic mice Nutr Res. 2022 Jul:103:47-58. doi: 10.1016/j.nutres.2022.03.011. (IF 2.767)
23. He-Yong Tang, Xi-Qiuyu Chen, Hao Wang, Hao-Ran Chu, Cai-Feng Zhu, Shun Huang, Meng-Ting Zhang, Guo-Ming Shen . Acupuncture relieves the visceral pain of diarrhea-predominant irritable bowel syndrome rats by regulating P2X4 expression Am J Transl Res. 2022 Aug 15;14(8):5563-5573. (IF 3.375)
24. Xiangrong Li, Jingying Xie, Dianyu Li, Hongshan Li, Yuhui Niu, Bei Wu, Yanmei Yang, Zhenfang Yan, Xiangbo Zhang, Lei Chen, Ruofei Feng . HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection Viruses. 2022 Aug 23;14(9):1851. doi: 10.3390/v14091851.
25. Xiaojin Liu, Hao Lv, Haibin Shen . Vitamin D enhances the sensitivity of breast cancer cells to the combination therapy of photodynamic therapy and paclitaxel Tissue Cell. 2022 Aug:77:101815. doi: 10.1016/j.tice.2022.101815. (IF 1.837)
26. Ji Cheng, Dianwen Xu, Lisha Chen, Wenjin Guo, Guiqiu Hu, Juxiong Liu, Shoupeng Fu . CIDEA Regulates De Novo Fatty Acid Synthesis in Bovine Mammary Epithelial Cells by Targeting the AMPK/PPARγ Axis and Regulating SREBP1 J Agric Food Chem. 2022 Sep 14;70(36):11324-11335. doi: 10.1021/acs.jafc.2c05226.
27. Zhihui Zhang, Yulin Kuang, Kui Ma, Yan Li, Xiaoming Liu, Yuru Shi, Xu Wu . Gclc overexpression inhibits apoptosis of bone marrow mesenchymal stem cells through the PI3K/AKT/Foxo1 pathway to alleviate inflammation in acute lung injury Int Immunopharmacol. 2022 Sep:110:109017. doi: 10.1016/j.intimp.2022.109017. (IF 3.943)
28. Rui-Chen Xu, Wen-Teng Miao, Jing-Yi Xu, Wen-Xin Xu, Ming-Ran Liu, Song-Tao Ding, Yu-Xin Jian, Yi-Han Lei, Ning Yan, Han-Deng Liu . Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice Nutrients. 2022 Oct 7;14(19):4163. doi: 10.3390/nu14194163. (IF 4.546)
29. Qiang Ding, Xiuhu Ding, Shuwen Xia, Fang Zhao, Kunlin Chen, Yong Qian, Shaoxian Cao, Zhiping Lin, Yundong Gao, Huili Wang, Jifeng Zhong . Bta-miR-6531 Regulates Calcium Influx in Bovine Leydig Cells and Is Associated with Sperm Motility Genes (Basel). 2022 Oct 3;13(10):1788. doi: 10.3390/genes13101788.
30. Lei Wang, Min Li, Cuiping Zhu, Aiping Qin, Jinchun Wang, Xianni Wei . The protective effect of Palmatine on depressive like behavior by modulating microglia polarization in LPS-induced mice Neurochem Res. 2022 Oct;47(10):3178-3191. doi: 10.1007/s11064-022-03672-3. (IF 3.038)
31. Jing Zhao, Huidan Lu, Danxia Xu, Ruiqi Sun, Chengyu Fang, Qiyu Zhao, Chang He, Yuwei Pan, Feng Xu, Tianna Jiang . Neutrophil membrane-coated nanoparticles for enhanced nanosecond pulsed electric field treatment of pancreatic cancer Int J Hyperthermia. 2022 Dec;39(1):1026-1035. doi: 10.1080/02656736.2022.2093994.
32. Ting Huyan, Lina Gao, Na Gao, Chaochao Wang, Wuli Guo, Xiaojie Zhou, Qi Li . miR-221-5p and miR-186-5p Are the Critical Bladder Cancer Derived Exosomal miRNAs in Natural Killer Cell Dysfunction Int J Mol Sci. 2022 Dec 2;23(23):15177. doi: 10.3390/ijms232315177. (IF 4.556)
33. Min Zhang, Caiping Wang, Rongning Wang, Jiean Xu, Zhefeng Wang, Jianlong Yan, Yongfeng Cai, Liangping Li, Yuqing Huo, Shaohong Dong . Adenosine kinase promotes post-infarction cardiac repair by epigenetically maintaining reparative macrophage phenotype J Mol Cell Cardiol. 2023 Jan:174:88-100. doi: 10.1016/j.yjmcc.2022.11.007.
34. Yi-Qi Ma, Qun-Qi Hu, Yu Rong Kang, Li-Qian Ma, Si-Ying Qu, Han-Zhi Wang, Yin-Mu Zheng, Si-Yi Li, Xiao-Mei Shao, Xiao-Yu Li, Han-Tong Hu, Yong-Liang Jiang, Jian-Qiao Fang, Xiao-Fen He . Electroacupuncture Alleviates Diabetic Neuropathic Pain and Downregulates p-PKC and TRPV1 in Dorsal Root Ganglions and Spinal Cord Dorsal Horn Evid Based Complement Alternat Med. 2023 Feb 3:2023:3333563. doi: 10.1155/2023/3333563.
35. Yiyi Ye, Ying Xie, Lixia Pei, Ziwei Jiang, Chunyu Wu, Sheng Liu . Platycodin D induces neutrophil apoptosis by downregulating PD-L1 expression to inhibit breast cancer pulmonary metastasis Int Immunopharmacol. 2023 Feb:115:109733. doi: 10.1016/j.intimp.2023.109733.
36. Hongyan Zhang, Lulu Xu, Junwei Xiong, Xinxin Li, Yindong Yang, Yong Liu, Chunfeng Zhang, Qiyu Wang, Jiajia Wang, Pengyu Wang, Xiaobin Wu, Xue Wang, Xiaofeng Zhu, Yanzhong Guan . Role of KCC2 in the Regulation of Brain-Derived Neurotrophic Factor on Ethanol Consumption in Rats Mol Neurobiol. 2023 Feb;60(2):1040-1049. doi: 10.1007/s12035-022-03126-5.
37. Qun-Qi Hu, Xiao-Fen He, Yi-Qi Ma, Li-Qian Ma, Si-Ying Qu, Han-Zhi Wang, Yu-Rong Kang, Lu-Hang Chen, Xiang Li, Bo-Yu Liu, Xiao-Mei Shao, Jun-Fan Fang, Yi Liang, Jian-Qiao Fang, Yong-Liang Jiang . Dorsal root ganglia P2X4 and P2X7 receptors contribute to diabetes-induced hyperalgesia and the downregulation of electroacupuncture on P2X4 and P2X7 Purinergic Signal. 2023 Mar;19(1):29-41. doi: 10.1007/s11302-022-09844-8.
38. Yanchao Gu, Jingjing Tang, Fuhua Zhang, Yichen Qu, Min Zhao, Mengyuan Li, Zhen Xie, Xiao Wang, Li Song, Zhengfan Jiang, Yao Wang, Xihui Shen, Lei Xu . Manganese potentiates lipopolysaccharide-induced innate immune responses and septic shock Int J Biol Macromol. 2023 Mar 1:230:123202. doi: 10.1016/j.ijbiomac.2023.123202.
39. Yilin Gao, Oumeng Song, Min Wang, Xin Guo, Guanfei Zhang, Xuyun Liu, Jiankang Liu, Lin Zhao . Hydrogen Protection Boosts the Bioactivity of Chrysanthemum morifolium Extract in Preventing Palmitate-Induced Endothelial Dysfunction by Restoring MFN2 and Alleviating Oxidative Stress in HAEC Cells Antioxidants (Basel). 2023 Apr 28;12(5):1019. doi: 10.3390/antiox12051019.
40. Shuzhao Zhuang, Aaron Russell, Yifan Guo, Yingying Xu, Weihua Xiao . IFN-γ blockade after genetic inhibition of PD-1 aggravates skeletal muscle damage and impairs skeletal muscle regeneration Cell Mol Biol Lett. 2023 Apr 4;28(1):27. doi: 10.1186/s11658-023-00439-8.
41. Shuo Wang, Jinqian Liu, Dong Cheng, Lehao Ren, Lixue Zheng, Fang Chen, Tao Zeng . Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice Toxicology. 2023 Apr:488:153487. doi: 10.1016/j.tox.2023.153487.
42. Bolin Zheng, Yijing He, Shuai Yin, Xu Zhu, Qing Zhao, Huiyi Yang, Zhaojie Wang, Rongrong Zhu, Liming Cheng . Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury Research (Wash D C). 2023 May 4:6:0135. doi: 10.34133/research.0135.
43. Chaoqun Tong, Jian Luo, Chaolu Xie, Junhong Wei, Guoqing Pan, Zeyang Zhou, Chunfeng Li . Characterization and Biological Activities of Melanin from the Medicinal Fungi Ophiocordyceps sinensis Int J Mol Sci. 2023 Jun 17;24(12):10282. doi: 10.3390/ijms241210282.
44. Xiaoyang Zhou, Weiyang Sun, Yu Zhang, Hongjing Gu, Ruixuan Wang, Peng Xie, Yunkai Zhu, Minyue Qiu, Xiaoyan Ding, Hui Wang, Yuwei Gao, Jintao Li . A novel hACE2 knock-in mouse model recapitulates pulmonary and intestinal SARS-CoV-2 infection Front Microbiol. 2023 Jun 6:14:1175188. doi: 10.3389/fmicb.2023.1175188.
45. Mingjie Liang, Lexun Wang, Weixuan Wang . The 15-hydroxyprostaglandin dehydrogenase inhibitor SW033291 ameliorates abnormal hepatic glucose metabolism through PGE2-EP4 receptor-AKT signaling in a type 2 diabetes mellitus mouse model Cell Signal. 2023 Aug:108:110707. doi: 10.1016/j.cellsig.2023.110707.
46. Sen Zeng, Wenhui Zhu, Zipeng Luo, Keke Wu, Zhimin Lu, Xiaowen Li, Weijun Wang, Wenshuo Hu, Yuwei Qin, Wenxian Chen, Lin Yi, Shuangqi Fan, Jinding Chen . Role of OGDH in Atophagy-IRF3-IFN-β pathway during classical swine fever virus infection Int J Biol Macromol. 2023 Sep 30:249:126443. doi: 10.1016/j.ijbiomac.2023.126443.
47. Miao Li, Hongyu Tang, Yuanhao Hu, Songtao Li, Pan Kang, Baihao Chen, Shaocong Li, Meng Zhang, Haibin Wang, Shaochuan Huo . Integrating network pharmacology and experimental verification strategies to reveal the active ingredients and molecular mechanism of Tenghuang Jiangu Capsule against osteoporosis Heliyon. 2023 Sep 4;9(9):e19812. doi: 10.1016/j.heliyon.2023.e19812.
48. Yuanyuan Zhong, Bin Wang, Wenjing Chen, Hongying Zhang, Jing Sun, Jingcheng Dong . Exploring the Mechanisms of Modified Bu-Shen-Yi-Qi Decoction for COPD-Related Osteoporosis Therapy via Transcriptomics and Network Pharmacology Approach Drug Des Devel Ther. 2023 Sep 6:17:2727-2745. doi: 10.2147/DDDT.S413532.
49. Shicheng Sun, Guoliang Qi, Hao Chen, Dong He, Dengzhen Ma, Yifan Bie, Linzong Xu, Bin Feng, Qi Pang, Hua Guo, Rui Zhang . Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications Cell Death Dis. 2023 Nov 18;14(11):754. doi: 10.1038/s41419-023-06282-1.
50. Sufei Song, Jixian Zheng, Dongmei Zhao, Anni Zheng, Ye Zhu, Qiuling Xu, Tao Liu . Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue Clin Proteomics. 2023 Dec 1;20(1):55. doi: 10.1186/s12014-023-09442-9.
51. Xin Qing, Renbin Dou, Peng Wang, Mengni Zhou, Chenchen Cao, Huiwen Zhang, Gaolin Qiu, Zhilai Yang, Jiqian Zhang, Hu Liu, Shasha Zhu, Xuesheng Liu . Ropivacaine-loaded hydrogels for prolonged relief of chemotherapy-induced peripheral neuropathic pain and potentiated chemotherapy J Nanobiotechnology. 2023 Dec 2;21(1):462. doi: 10.1186/s12951-023-02230-5.
52. Fuqiang Yao, Minghao Xu, Lingjun Dong, Xiao Shen, Yujie Shen, Yisheng Jiang, Ting Zhu, Chu Zhang, Guangmao Yu . Sinomenine attenuates pulmonary fibrosis by downregulating TGF-β1/Smad3, PI3K/Akt and NF-κB signaling pathways BMC Pulm Med. 2024 May 10;24(1):229. doi: 10.1186/s12890-024-03050-5.
53. Xiaoao Feng, Dejing Yin, Tian Fang, Chao Zhao, Jun Yue, Erpeng Zhu, Zhentao Cheng . Fowl adenovirus serotype 4 (FAdV-4) infection induces inflammatory responses in chicken embryonic cardiac fibroblasts via PI3K/Akt and IκBα/NF-κB signaling pathways Res Vet Sci. 2024 Aug:176:105349. doi: 10.1016/j.rvsc.2024.105349.