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文献和实验Measuring Ca2+ Changes in Multiwell Format Using the Fluorometric Imaging Plate Reader
The Fluorometric Imaging Plate Reader (FLIPR�; Molecular Devices, Sunnyvale, CA; see Fig. 1 ) has made a significant contribution to drug discovery programs in the pharmaceutical industry since the first commercial instruments were introduced
G protein-coupled receptors (GPCRs) are the target of approximately 40% of all approved drugs and continue to represent a significant portion of drug discovery portfolios across the pharmaceutical industry. As a result, GPCRs are the focus
Measuring Ca2+ Changes in Multiwell Format Using the Fluorometric Imaging Plate Reader (FLIPR)
The Fluorometric Imaging Plate Reader (FLIPR) has made a significant contribution to drug discovery programs. The key advantage of FLIPR over conventional plate readers is the ability to measure fluorescence emission from multiple wells (96
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