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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
7-Allyl-8-oxoguanosine; RWJ 21757
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
121288-39-9
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥299.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥400.0 |
| 规格： | 10 mg | 产品价格： | ￥650.0 |
| 规格： | 25 mg | 产品价格： | ￥1250.0 |
| 规格： | 50 mg | 产品价格： | ￥1900.0 |
| 规格： | 100 mg | 产品价格： | ￥2850.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Loxoribine
CAS No. : 121288-39-9
MCE 国际站：Loxoribine
产品活性：Loxoribine (7-Allyl-8-oxoguanosine) 是一种鸟苷类似物，具有抗病毒和抗肿瘤活性。Loxoribine 是一种口服生物可利用、选择性的 TLR7 激动剂。
研究领域：Immunology/Inflammation | Anti-infection
作用靶点：Toll-like Receptor (TLR) | Influenza Virus
In Vitro: Loxoribine induces maturation of human monocyte-derived dendritic cells DCs and stimulates their Th-1- and Th-17-polarizing capability.
Loxoribine (250 μM; 48 hours) stimulates maturation of MoDCs as shown by up-regulation of CD80, CD83, CD40, CD54 and CCR7.
loxoribine activates cells of the innate immune system selectively via the Toll-like receptor (TLR) 7/MyD88-dependent signaling pathway.
In Vivo: Loxoribine (2 mg; s.c.or i.v.) activates murine natural killer (NK) cells in vivo.
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