Purified HERPUD1 mouse monoclo

gene_symbol：HERPUD1
predicted_size：43.4 kDa
Uniprot ID：Q1511
description：Purified HERPUD1 mouse monoclonal antibody, clone OTI1A2 (formerly 1A2)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
immunogen：Full length human recombinant protein of human HERPUD1(NP_001010989) produced in HEK293T cell.
recommended_dilution：WB 1:400~4000, IHC 1:150, IF 1:100
predicted_size：43.4 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：IF, IHC, WB
reactivities：Human, Rat, Mouse