PTPRC mouse monoclonal antibod

gene_symbol：PTPRC
predicted_size：147.1 kDa
Uniprot ID：P8575
description：PTPRC mouse monoclonal antibody, clone OTI2E7 (formerly 2E7)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
immunogen：Full length human recombinant protein of human PTPRC(NP_002829) produced in HEK293T cell.
recommended_dilution：WB 1:400~4000, IHC 1:500, IF 1:100, FLOW 1:50
predicted_size：147.1 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：FC, IF, IHC, WB
reactivities：Human