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- P6006-5μg
- 2025年08月26日
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5μg
| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| P6006-5μg | Recombinant Murine GM-CSF | 5μg | 646.00元 |
| P6006-20μg | Recombinant Murine GM-CSF | 20μg | 1613.00元 |
| P6006-100μg | Recombinant Murine GM-CSF | 100μg | 5140.00元 |
| P6006-1mg | Recombinant Murine GM-CSF | 1mg | 20548.00元 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Mouse | 12981 | P01587 | E. coli | 124aa | 14.1kDa | － |
| About this Antibody | |
| Name | Recombinant Murine GM-CSF (Recombinant Murine Granulocyte-Macrophage Colony Stimulating Factor; rMuGM-CSF)；Recombinant Mouse GM-CSF ; 重组小鼠粒细胞巨噬细胞集落刺激因子 |
| Synonyms | CSF2; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; GM-CSF; GMCSFgranulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; Molgramostin; molgramostin; sargramostim; Sargramostim |
| Purity | >98% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine FDC-P1 cells is less than 0.05ng/ml, corresponding to a specific activity of >2.0×107IU/mg. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered solution in PBS, pH7.4. |
| Endotoxin | Less than 1EU/μg of rMuGM-CSF as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is secreted by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation. It was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors and has functions of stimulates the growth and differentiation of hematopoietic precursor cells from various lineages. GM-CSF has also been reported to have a functional role on non-hematopoietic cells and can induce human endothelial cells to migrate and proliferate. Additionally, it can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. Mouse GM-CSF shares 54% sequences identity with human GM-CSF, but has no biological effects across species. GM-CSF is used as a medication to stimulate the production of white blood cells following chemotherapy and has also recently been evaluated in clinical trials for its potential as a vaccine adjuvant in HIV-infected patients. |
| Amino Acid Sequence | APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK PGQK |
包装清单:
| 产品编号 | 产品名称 | 包装 |
| P6006-5μg | Recombinant Murine GM-CSF | 5μg |
| P6006-20μg | Recombinant Murine GM-CSF | 20μg |
| P6006-100μg | Recombinant Murine GM-CSF | 100μg |
| P6006-1mg | Recombinant Murine GM-CSF | 1mg |
| - | 说明书 | 1份 |
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
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