Connexin 26 Rabbit pAb(bs-21812R)-50ul/100ul/200ul

Connexin 26 Rabbit pAb(bs-2181

2R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-21812R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号 bs-21812R
    英文名称 Connexin 26 Rabbit pAb
    中文名称 间隙连接蛋白26/GJB2抗体
    英文别名 cx26; DFNA3; DFNB1; HID; KID; NSRD1; Connexin26; Connexin-26; GJB2; PPK; CXB2_HUMAN.
    产品应用 WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 Mouse (Rat)
    抗体来源 Rabbit
    免疫原 KLH conjugated synthetic peptide derived from mouse Connexin 26
    亚型 IgG
    性状 Liquid
    克隆类型 Polyclonal
    理论分子量 26 kDa
    浓度 1mg/ml
    储存液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Sensory System > Auditory system

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Gap Junctions

    亚细胞定位 Cell membrane. Cell junction, gap junction.
    组织特异性 Expressed in the heart and fetal cochlea.
    翻译后修饰 Belongs to the connexin family. Beta-type (group I) subfamily.
    相似性 Belongs to the connexin family. Alpha-type (group II) subfamily.
    功能 One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neiG‌‌HBoring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
    保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料 Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap junction proteins or connexins) play crucial functional roles associated with these channels. Immunohistochemical staining of human cochlear cells demonstrated high levels of GJB2 expression. Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.

     

    应用 推荐稀释比例
    {WB} {1:500-2000}

     

    Sample:
    Placenta (Mouse) Lysate at 40 ug
    Primary: Anti-Connexin 26 (bs-21812R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 26 kD
    Observed band size: 26 kD

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