重组人PTH1-34北京价格

特别提示：包括重组人PTH1-34在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人PTH1-34
英文名称：Recombinant Human Parathyroid Hormone 1-34
产品货号：GS4431
产品规格：20μg

分子量：Approximately 4.1kDa,a single non-glycosylated polypeptide chain containing 34 amino acids.
储存条件：冷冻（-20℃）

概述

Parathyroid hormone(PTH)is a single polypeptide of 84 amino acids.It is a critical hormone in the regulation of Ca2+ homeostasis,secreted by the parathyroid glands,which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts,indirectly promote increased intestinal absorption of calcium,and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates.It is a major regulator of bone metabolism.Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low.The amino terminal(1-34)fragment of parathyroid hormone,called PTH(1-34)reproduces all the activity of the full length mature hormone and has been used therapeutically for treatment of osteoporosis.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50ng/ml,corresponding to a specific activity of>2.0×104 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.0.
内毒素	Less than 1EU/μg of rHuPTH1-34 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNF

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