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IgM Heavy Chain Antibody

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  • ¥5832.53
  • nsjbio
  • 2025年07月12日
  • Rabbit
  • Human. Other species not tested.
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      Rabbit IgG, kappa

    • 克隆性

      单克隆

    • 适应物种

      Human. Other species not tested.

    • 宿主

      Rabbit

    • 规格

      7 ml

    产品类型:
    Primary antibody
    纯化方法:
    Purified
    通用信息:
    Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
    产品描述:
    The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD on their surface. During an antibody response, activated B cells can switch to the expression of individual downstream heavy chain C region genes by a process of somatic recombination known as isotype switching. In addition, secreted Ig forms that act as antibodies can be produced by alternative RNA processing of the heavy chain C region sequences. Although the membrane forms of all Ig isotypes are monomeric, secreted IgM forms pentamers, and occasionally hexamers, in plasma. [RefSeq]
    联系方式:

    生物商城:http://www.annoron.com

    办公电话:010-56256916

    官方售后:400-965-8633

    企业 QQ:3212874516、3198592576

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    图标文献和实验
    相关实验
    • Production of Chimeric Heavy-Chain Antibodies

      of fragment crystallizable (Fc), which is known to be crucial for a long serum half-life through binding to FcRn and antibody-mediated cell killing through binding to Fcγ receptors and complement. Single-domain antibodies (sdAbs) derived from camelid heavy

    • Introduction to Heavy Chain Antibodies and Derived Nanobodies

      The immune response of infected or immunized dromedaries contains a diverse repertoire of conventional and heavy chain-only antibodies, both functional in antigen binding. By definition, a heavy chain antibody is devoid of a light chain

    • Stable Expression of Chimeric Heavy Chain Antibodies in CHO Cells

      Camelid single domain antibodies fused to noncamelid Fc regions, also called chimeric heavy chain antibodies (cHCAb), offer great potential as therapeutic and diagnostic candidates due to their relatively small size (80 kDa) and intact Fc

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