Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
单克隆
库存:
100
宿主:
Mouse
抗体名:
BIG3
规格:
100 μl
分子量:
36.6kDa
细胞定位:
Antigen Cellular Localization:Nucleus
形式:
Liquid. In PBS containing 0.02% sodium azide.
参考文献:
1. Mol Syst Biol. 2007;3:89. 2. J Biol Chem. 2008 Nov 21;283(47):32162-75.
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality WDR5 antibody.
功能:
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
总结: