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动物ECG/EMG系统采用高精度电极,旨在采集动物高真表面心电及肌电信号,为心血管及神经科学等研究提供可靠的数据支持。
系统由数据采集器、生物电放大器、分析软件(LabScribe 基础软件及ECG 专用分析模块)及心电导联线和电极组成,可实现对多种动物进行多通道实时的ECG/EMG数据采集和分析。
主要特点:
生物电放大器
IX-BIO8:8 通道生物电采集器/放大器,可于同只实验动物采集I、II 导联ECG 及6 通道EMG 或者8 通道EMG(III、aVL、aVR、aVF 导联由I、II导联分析得出)
iWire-ECG12:12 导联ECG 放大器,可于同只实验动物采集全部肢体导联及胸导联ECG(采集I、II 导联,III、aVL、aVR、aVF 导联由I、II 导联分析得出)
LabScribe 软件
LabScribe 是一款功能强大的数据采集及分析软件,其具有直观的、用户友好的操作屏幕用于显示、校准及分析数据,在100k/s 的采样率条件下,最多可同时呈现128 个通道数据。软件兼容Windows 及OSX 系统,支持Dadisp、Python、
MatLab、LabView 及C++等语言及数据格式。预设的通用数据分析模式使数据处理过程快速而简便,对于部分研究领域,LabScribe 还有专用分析模式,功能全面,满足各种不同实验需要。
LabScribe 心电分析模块具有以下特点:
心电导联线:
其他心电测量系统:
小动物心电、肌电采集与分析系统参考文献:
1. Fang, Yin et al. “Micelle-enabled self-assembly of porous and monolithic carbon membranes for bioelectronic interfaces.” Nature nanotechnology vol. 16,2 (2021): 206-213. doi:10.1038/s41565-020-00805-z
2. Usseglio, Giovanni et al. “Control of Orienting Movements and Locomotion by Projection-Defined Subsets of Brainstem V2a Neurons.” Current biology : CB vol. 30,23 (2020): 4665-4681.e6. doi:10.1016/j.cub.2020.09.014
3. Marshall, Michael S et al. “Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.” Molecular therapy : the journal of the American Society of Gene Therapy vol. 26,3 (2018): 874-889. doi:10.1016/j.ymthe.2018.01.009
4. Moyano, Ana Lis et al. “microRNA-219 Reduces Viral Load and Pathologic Changes in Theiler's Virus-Induced Demyelinating Disease.” Molecular therapy : the journal of the American Society of Gene Therapy vol. 26,3 (2018): 730-743. doi:10.1016/j.ymthe.2018.01.008
5. Chen, Shih-Heng et al. “An electrospun nerve wrap comprising Bletilla striata polysaccharide with dual function for nerve regeneration and scar prevention.” Carbohydrate polymers vol. 250 (2020): 116981. doi:10.1016/j.carbpol.2020.116981
6. Hérent, Coralie et al. “Absent phasing of respiratory and locomotor rhythms in running mice.” eLife vol. 9 e61919. 1 Dec. 2020, doi:10.7554/eLife.61919
7. Tsai, Pei-Jiun et al. “Xenografting of human umbilical mesenchymal stem cells from Wharton's jelly ameliorates mouse spinocerebellar ataxia type 1.” Translational neurodegeneration vol. 8 29. 5 Sep. 2019, doi:10.1186/s40035-019-0166-8
8. Lienemann, Samuel et al. “Stretchable gold nanowire-based cuff electrodes for low-voltage peripheral nerve stimulation.” Journal of neural engineering vol. 18,4 10.1088/1741-2552/abfebb. 25 May. 2021, doi:10.1088/1741-2552/abfebb
9. Gregory, Nicholas S et al. “ASIC3 Is Required for Development of Fatigue-Induced Hyperalgesia.” Molecular neurobiology vol. 53,2 (2016): 1020-1030. doi:10.1007/s12035-014-9055-410. Bowtell, Joanna L et al. “Acute physiological and performance responses to repeated sprints in varying degrees of hypoxia.” Journal of science and medicine in sport vol. 17,4 (2014): 399-403. doi:10.1016/j.jsams.2013.05.016
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1. Fang, Yin et al. “Micelle-enabled self-assembly of porous and monolithic carbon membranes for bioelectronic interfaces.” Nature nanotechnology vol. 16,2 (2021): 206-213. doi:10.1038/s41565-020-00805-z
2. Usseglio, Giovanni et al. “Control of Orienting Movements and Locomotion by Projection-Defined Subsets of Brainstem V2a Neurons.” Current biology : CB vol. 30,23 (2020): 4665-4681.e6. doi:10.1016/j.cub.2020.09.014
3. Marshall, Michael S et al. “Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.” Molecular therapy : the journal of the American Society of Gene Therapy vol. 26,3 (2018): 874-889. doi:10.1016/j.ymthe.2018.01.009
4. Moyano, Ana Lis et al. “microRNA-219 Reduces Viral Load and Pathologic Changes in Theiler's Virus-Induced Demyelinating Disease.” Molecular therapy : the journal of the American Society of Gene Therapy vol. 26,3 (2018): 730-743. doi:10.1016/j.ymthe.2018.01.008
5. Chen, Shih-Heng et al. “An electrospun nerve wrap comprising Bletilla striata polysaccharide with dual function for nerve regeneration and scar prevention.” Carbohydrate polymers vol. 250 (2020): 116981. doi:10.1016/j.carbpol.2020.116981
6. Hérent, Coralie et al. “Absent phasing of respiratory and locomotor rhythms in running mice.” eLife vol. 9 e61919. 1 Dec. 2020, doi:10.7554/eLife.61919
7. Tsai, Pei-Jiun et al. “Xenografting of human umbilical mesenchymal stem cells from Wharton's jelly ameliorates mouse spinocerebellar ataxia type 1.” Translational neurodegeneration vol. 8 29. 5 Sep. 2019, doi:10.1186/s40035-019-0166-8
8. Lienemann, Samuel et al. “Stretchable gold nanowire-based cuff electrodes for low-voltage peripheral nerve stimulation.” Journal of neural engineering vol. 18,4 10.1088/1741-2552/abfebb. 25 May. 2021, doi:10.1088/1741-2552/abfebb
9. Gregory, Nicholas S et al. “ASIC3 Is Required for Development of Fatigue-Induced Hyperalgesia.” Molecular neurobiology vol. 53,2 (2016): 1020-1030. doi:10.1007/s12035-014-9055-410. Bowtell, Joanna L et al. “Acute physiological and performance responses to repeated sprints in varying degrees of hypoxia.” Journal of science and medicine in sport vol. 17,4 (2014): 399-403. doi:10.1016/j.jsams.2013.05.016
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