A recombinant human partial protein corresponding to amino acids 23-119 from the human CD3 epsilon chain were used as the immunogen for the CD3e antibody.
亚型:
Mouse IgG1, kappa
克隆性:
单克隆
适应物种:
Human. Other species not tested.
宿主:
Mouse
规格:
100ug
产品类型:
Primary antibody
纯化方法:
Purified
通用信息:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
产品描述:
This antibody recognizes the epsilon chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
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