Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
单克隆
适应物种:
Human, Rat
库存:
100
宿主:
Rabbit
应用范围:
WB, IHC
靶点:
A synthetic peptide corresponding to residues near the N-terminal of human CD90 was used as an immunogen.
规格:
100 μl
分子量:
17935 Da
细胞定位:
Antigen Cellular Localization:Cell membrane; Lipid-anchor, GPI-anchor
形式:
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
参考文献:
1. The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2008) 2. TA Rege, JS Hagood., The FASEB Journal 20:1045-1054, 2006 3. ZF Yang et al., Cancer Cell 3(2):153-66, 2008.
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality CD90 antibody.
功能:
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
总结:
CD90 (Cluster of Differentiation 90, Thy-1) is a heavily N-glycosylated GPI linked cell surface protein member of the immunoglobulin (Ig) superfamily. As a smallest member of family, CD90 may play a role in cell-to-cell and cell-to-lignand interactions during synaptogensis and other neuron related activities (e.g. neurite outgrowth, nerve regeneration) (1). In developing nervous tissue, CD90 is involved in axon growth regulation by halting axon growth in mature axon via its interaction with intergin-beta-3 on mature astrocytes. Additionally, CD90 has been linked to apoptosis, adhesion, migration, cancer (including cancer stem cells), and fibrosis (2). As a major marker for hematopoietic stem cells (HSCs), CD90 mediates differentiation of HSCs. In stem cancer cell research, CD90+ cells in the hepatocellular carcinoma (HCC) have been shown to display tumorgenic capacity (3).
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