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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
426834-69-7
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1894.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥571.0 |
| 规格： | 5 mg | 产品价格： | ￥1500.0 |
| 规格： | 10 mg | 产品价格： | ￥2400.0 |
| 规格： | 25 mg | 产品价格： | ￥4225.0 |
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NS5806
CAS No. : 426834-69-7
MCE 国际站：NS5806
产品活性：NS5806 是一种有效的钾电流激活剂，可增加 KV4.3/KChIP2 峰值电流幅度，EC50 为 5.3 μM。NS5806 会在包含 KChIP2 的通道复合体中降低 KV4.3 和 KV4.2 电流衰减。
研究领域：Membrane Transporter/Ion Channel
作用靶点：Potassium Channel
In Vitro: NS5806 (10 μM) induces a 65% increase of KV4.3/KChIP2/DPP6 peak current amplitudes concentration-dependently and the time course of inactivation (τ) is slowed with an EC50 value of 25.4 μM in CHO-K1 cells.
?NS5806 activates canine transient outward potassium current (Ito) with an IC50 of 40.7 nM and an EC50 of 1.6 nM for inhibition and stimulation on rabbit, respectively.
?NS5806 (10-100 nM) has concentration-dependent effects on ventricular and atrial Ito.
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文献和实验3.00 2.00 12.00 GAACCCAGGAGGCAGAGC PRODUCT SIZE: 1081, PAIR ANY COMPL: 5.00, PAIR 3' COMPL: 2.00 TARGETS (start, len)*: 167,993 Statistics con too in in no tm tm high high high high sid many tar excl bad GC too too any 3' lib poly end ered Ns
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stirrer (see Step 32) Microcentrifuge tubes (1.5 ml and 2.0 ml) Chromatin immunoprecipitations and incubations with Protein A (G) Sepharose (Steps 44-69) are performed in microcentrifuge tubes. These tubes may be siliconized beforehand (e
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