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CD3e (T-Cell Marker) Antibody

- Without BSA
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  • $495
  • Leading Biology
  • 2025年10月13日
  • IF, FC
  • Mouse
  • Human, Monkey
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      Mouse / IgG2a, kappa

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human, Monkey

    • 库存

      100

    • 宿主

      Mouse

    • 应用范围

      IF, FC

    • 规格

      100 μg

    Prouduct: We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD3e (T-Cell Marker) Antibody - Without BSA. Functiong: The CD3 complex mediates signal transduction. Summary: Recognizes the -chain of CD3 (Workshop V; Code: CD03.09), which consists of five different polypeptide chains (designated as γ, δ, ε, ζ, and η) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

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    图标文献和实验
    相关实验
    • T-Cell Activation Using mAb to CD3

      splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16

    • In Vitro T Cell Activation

        In Vitro T Cell Activation Introduction Mature T cells recognize and respond to the antigen/MHC complex through their antigen-specific receptors (TCR). The most immediate consequence of TCR activation is the initiation

    • T cell Activation Protocol

      cell suspension   20 minutes to set up the assay   2-4 days incubation         Method:       ANTIBODY COATING OF THE ASSAY PLATE:   1) Prepare a 5-10 ug/ml solution of anti-CD3e (145-2C

    图标技术资料

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