- ￥1125 - 3750
- Leading Biology
- AMM02473G
- 美国
- 2025年10月03日
- IHC-P, WB
- Mouse
- H, M, Rat
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![USP44 Mouse Monoclonal Antibody [Clone ID: LBI1D7]](https://img1.dxycdn.com/2022/0707/344/1496323853485278553-14.jpg!wh200)
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
Proliferating cell nuclear antigen, PCNA, Cyclin, PCNA
- 浓度：
Affinity Purification
- 应用范围：
IHC-P, WB
- 宿主：
Mouse
- 适应物种：
H, M, Rat
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 克隆性：
Monoclonal
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原：
This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
- 规格：
400ul/200ul/100ul
| 规格： | 400ul | 产品价格： | ￥3750.0 |
|---|---|---|---|
| 规格： | 200ul | 产品价格： | ￥2000.0 |
| 规格： | 100ul | 产品价格： | ￥1125.0 |
细胞定位：Nucleus Note=Colocalizes with CREBBP, EP300 and POLD1 to sites of DNA damage (PubMed:24939902). Forms nuclear foci representing sites of ongoing DNA replication and vary in morphology and number during S phase (PubMed:15543136). Co-localizes with SMARCA5/SNF2H and BAZ1B/WSTF at replication foci during S phase (PubMed:15543136). Together with APEX2, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents.
功能：Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways (PubMed:24939902). Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion (PubMed:24695737).
稀释方法：IHC-P--1:100~500 IHC--1:2000 WB--1:2000
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文献和实验Flow Cytometric Detection of Proliferation-Associated Antigens, PCNA and Ki-67
The rapid evolution of monoclonal antibody (MAb) technology has resulted in an ever-growing repertoire of proteins becoming accessible for study using immunohistochemical techniques. Nuclear antigens represent a class of proteins
【求助】谢谢，请问ki67、PCNA、P53的英文全称是什么？
in conserving stability by preventing genome mutation. PCNA：Proliferating Cell Nuclear Antigen Antigen identified by monoclonal antibody Ki-67 also known as Ki-67 or MKI67 is a protein which in humans is encoded by the MKI67 gene 做科研要学会查，不要不懂就问
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人增殖细胞核抗原 (PCNA)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 PCNA 单抗包被于酶标板上，标准品和样品中的 PCNA与单抗结合，加入生物素化的抗人 PCNA ，形成免疫
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