![Phospho-rat TSC2 (T1373) Antibody [APR05316G]](https://custom.dxycdn.com/trademd/upload/pic/2016/09/12/A1473665352663g9fqz4svch.jpg!small.t.1)
- ￥1375 - 5000
- Leading Biology
- APR05316G
- 美国
- 2025年09月30日
- DB
- Rabbit
- Rat
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- 详细信息
- 技术资料
- 靶点：
Tuberin, Tuberous sclerosis 2 protein homolog, Tsc2
- 浓度：
Affinity Purification
- 应用范围：
DB
- 宿主：
Rabbit
- 适应物种：
Rat
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 克隆性：
Polyclonal
- 保存条件：
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 形态：
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
- 免疫原：
This rat TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1373 of rat TSC2.
- 规格：
400 µl/200 µl/100 µl/50 µl
| 规格： | 400 µl | 产品价格： | ￥5000.0 |
|---|---|---|---|
| 规格： | 200 µl | 产品价格： | ￥3250.0 |
| 规格： | 100 µl | 产品价格： | ￥2250.0 |
| 规格： | 50 µl | 产品价格： | ￥1375.0 |
功能：In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1 (By similarity). May also play a role in microtubule-mediated protein transport (PubMed:16707451). Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 (PubMed:9045618).
总结：Tissue Location: CNS, uterus, heart, skeletal muscle, kidney and spleen
稀释方法：DB--1:500
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